000 02618 a2200781 4500
005 20250514221750.0
264 0 _c20050712
008 200507s 0 0 eng d
022 _a0021-9258
024 7 _a10.1074/jbc.M501130200
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aNakaya, Yoshifumi
245 0 0 _aRandom mutagenesis of presenilin-1 identifies novel mutants exclusively generating long amyloid beta-peptides.
_h[electronic resource]
260 _bThe Journal of biological chemistry
_cMay 2005
300 _a19070-7 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAllosteric Site
650 0 4 _aAmyloid beta-Peptides
_xchemistry
650 0 4 _aAmyloid beta-Protein Precursor
_xchemistry
650 0 4 _aAnimals
650 0 4 _aBinding Sites
650 0 4 _aBlotting, Western
650 0 4 _aCell Line
650 0 4 _aCell Membrane
_xmetabolism
650 0 4 _aCentrifugation, Density Gradient
650 0 4 _aDNA, Complementary
_xmetabolism
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aEnzyme-Linked Immunosorbent Assay
650 0 4 _aFibroblasts
_xmetabolism
650 0 4 _aGlycerol
_xpharmacology
650 0 4 _aHumans
650 0 4 _aImmunoblotting
650 0 4 _aImmunohistochemistry
650 0 4 _aImmunoprecipitation
650 0 4 _aMass Spectrometry
650 0 4 _aMembrane Proteins
_xgenetics
650 0 4 _aMice
650 0 4 _aMutagenesis
650 0 4 _aMutation
650 0 4 _aMutation, Missense
650 0 4 _aPresenilin-1
650 0 4 _aProtein Isoforms
650 0 4 _aProtein Structure, Tertiary
650 0 4 _aProteins
_xchemistry
650 0 4 _aReceptors, Notch
650 0 4 _aRetroviridae
_xgenetics
650 0 4 _aSubcellular Fractions
_xmetabolism
650 0 4 _aSulindac
_xanalogs & derivatives
650 0 4 _aTransfection
650 0 4 _aUp-Regulation
700 1 _aYamane, Takuya
700 1 _aShiraishi, Hirohisa
700 1 _aWang, Hua-Qin
700 1 _aMatsubara, Etsuro
700 1 _aSato, Toru
700 1 _aDolios, Georgia
700 1 _aWang, Rong
700 1 _aDe Strooper, Bart
700 1 _aShoji, Mikio
700 1 _aKomano, Hiroto
700 1 _aYanagisawa, Katsuhiko
700 1 _aIhara, Yasuo
700 1 _aFraser, Paul
700 1 _aSt George-Hyslop, Peter
700 1 _aNishimura, Masaki
773 0 _tThe Journal of biological chemistry
_gvol. 280
_gno. 19
_gp. 19070-7
856 4 0 _uhttps://doi.org/10.1074/jbc.M501130200
_zAvailable from publisher's website
999 _c15437464
_d15437464