000 01877 a2200493 4500
005 20250514220715.0
264 0 _c20050606
008 200506s 0 0 eng d
022 _a0306-4522
024 7 _a10.1016/j.neuroscience.2004.11.038
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aButler, M
245 0 0 _aSpinal distribution and metabolism of 2'-O-(2-methoxyethyl)-modified oligonucleotides after intrathecal administration in rats.
_h[electronic resource]
260 _bNeuroscience
_c2005
300 _a705-15 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAnimals
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Administration Schedule
650 0 4 _aGanglia, Spinal
_xanatomy & histology
650 0 4 _aGlial Fibrillary Acidic Protein
_xmetabolism
650 0 4 _aImmunohistochemistry
_xmethods
650 0 4 _aInjections, Spinal
_xmethods
650 0 4 _aMale
650 0 4 _aOligonucleotides, Antisense
_xadministration & dosage
650 0 4 _aPhosphopyruvate Hydratase
_xmetabolism
650 0 4 _aProtein Kinase C
_xgenetics
650 0 4 _aProtein Kinase C-alpha
650 0 4 _aRNA, Messenger
_xbiosynthesis
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aReverse Transcriptase Polymerase Chain Reaction
_xmethods
650 0 4 _aSpinal Cord
_xanatomy & histology
650 0 4 _aThionucleotides
_xadministration & dosage
650 0 4 _aTime Factors
650 0 4 _aTissue Distribution
700 1 _aHayes, C S
700 1 _aChappell, A
700 1 _aMurray, S F
700 1 _aYaksh, T L
700 1 _aHua, X-Y
773 0 _tNeuroscience
_gvol. 131
_gno. 3
_gp. 705-15
856 4 0 _uhttps://doi.org/10.1016/j.neuroscience.2004.11.038
_zAvailable from publisher's website
999 _c15405488
_d15405488