| 000 | 02005 a2200625 4500 | ||
|---|---|---|---|
| 005 | 20250514220456.0 | ||
| 264 | 0 | _c20050712 | |
| 008 | 200507s 0 0 eng d | ||
| 022 | _a1087-0156 | ||
| 024 | 7 |
_a10.1038/nbt1067 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aHoet, René Michael | |
| 245 | 0 | 0 |
_aGeneration of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity. _h[electronic resource] |
| 260 |
_bNature biotechnology _cMar 2005 |
||
| 300 |
_a344-8 p. _bdigital |
||
| 500 | _aPublication Type: Letter | ||
| 650 | 0 | 4 | _aAntibody Affinity |
| 650 | 0 | 4 | _aAntibody Formation |
| 650 | 0 | 4 |
_aComplementarity Determining Regions _xgenetics |
| 650 | 0 | 4 |
_aGenetic Variation _xgenetics |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aImmunoglobulin Fab Fragments _xbiosynthesis |
| 650 | 0 | 4 | _aPeptide Library |
| 650 | 0 | 4 | _aProtein Binding |
| 650 | 0 | 4 |
_aProtein Engineering _xmethods |
| 650 | 0 | 4 |
_aRecombination, Genetic _xgenetics |
| 650 | 0 | 4 | _aTissue Donors |
| 700 | 1 | _aCohen, Edward H | |
| 700 | 1 | _aKent, Rachel Baribault | |
| 700 | 1 | _aRookey, Kristin | |
| 700 | 1 | _aSchoonbroodt, Sonia | |
| 700 | 1 | _aHogan, Shannon | |
| 700 | 1 | _aRem, Louise | |
| 700 | 1 | _aFrans, Nicolas | |
| 700 | 1 | _aDaukandt, Marc | |
| 700 | 1 | _aPieters, Henk | |
| 700 | 1 | _avan Hegelsom, Rob | |
| 700 | 1 | _aNeer, Nicole Coolen-van | |
| 700 | 1 | _aNastri, Horacio G | |
| 700 | 1 | _aRondon, Isaac J | |
| 700 | 1 | _aLeeds, Jennifer A | |
| 700 | 1 | _aHufton, Simon E | |
| 700 | 1 | _aHuang, Lili | |
| 700 | 1 | _aKashin, Irina | |
| 700 | 1 | _aDevlin, Mary | |
| 700 | 1 | _aKuang, Guannan | |
| 700 | 1 | _aSteukers, Mieke | |
| 700 | 1 | _aViswanathan, Malini | |
| 700 | 1 | _aNixon, Andrew E | |
| 700 | 1 | _aSexton, Daniel J | |
| 700 | 1 | _aHoogenboom, Hennie R | |
| 700 | 1 | _aLadner, Robert Charles | |
| 773 | 0 |
_tNature biotechnology _gvol. 23 _gno. 3 _gp. 344-8 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1038/nbt1067 _zAvailable from publisher's website |
| 999 |
_c15398075 _d15398075 |
||