000 | 02154 a2200601 4500 | ||
---|---|---|---|
005 | 20250514220237.0 | ||
264 | 0 | _c20050405 | |
008 | 200504s 0 0 eng d | ||
022 | _a0022-2623 | ||
024 | 7 |
_a10.1021/jm0491849 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aBaron, Bruce M | |
245 | 0 | 0 |
_aCoMFA, synthesis, and pharmacological evaluation of (E)-3-(2-carboxy-2-arylvinyl)-4,6-dichloro-1H-indole-2-carboxylic acids: 3-[2-(3-aminophenyl)-2-carboxyvinyl]-4,6-dichloro-1H-indole-2-carboxylic acid, a potent selective glycine-site NMDA receptor antagonist. _h[electronic resource] |
260 |
_bJournal of medicinal chemistry _cFeb 2005 |
||
300 |
_a995-1018 p. _bdigital |
||
500 | _aPublication Type: Journal Article | ||
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aAnticonvulsants _xchemical synthesis |
650 | 0 | 4 | _aBinding Sites |
650 | 0 | 4 |
_aCarboxylic Acids _xchemical synthesis |
650 | 0 | 4 |
_aCyclic GMP _xbiosynthesis |
650 | 0 | 4 |
_aGlycine _xmetabolism |
650 | 0 | 4 | _aIn Vitro Techniques |
650 | 0 | 4 |
_aIndoles _xchemical synthesis |
650 | 0 | 4 | _aMale |
650 | 0 | 4 | _aMice |
650 | 0 | 4 | _aMice, Inbred DBA |
650 | 0 | 4 | _aModels, Molecular |
650 | 0 | 4 |
_aNeuroprotective Agents _xchemical synthesis |
650 | 0 | 4 |
_aPhenylacetates _xchemical synthesis |
650 | 0 | 4 | _aQuantitative Structure-Activity Relationship |
650 | 0 | 4 | _aRadioligand Assay |
650 | 0 | 4 | _aRats |
650 | 0 | 4 | _aRats, Sprague-Dawley |
650 | 0 | 4 |
_aReceptors, N-Methyl-D-Aspartate _xantagonists & inhibitors |
650 | 0 | 4 |
_aSeizures _xetiology |
650 | 0 | 4 | _aStereoisomerism |
650 | 0 | 4 |
_aStroke _xdrug therapy |
700 | 1 | _aCregge, Robert J | |
700 | 1 | _aFarr, Robert A | |
700 | 1 | _aFriedrich, Dirk | |
700 | 1 | _aGross, Raymond S | |
700 | 1 | _aHarrison, Boyd L | |
700 | 1 | _aJanowick, David A | |
700 | 1 | _aMatthews, Donald | |
700 | 1 | _aMcCloskey, Timothy C | |
700 | 1 | _aMeikrantz, Scott | |
700 | 1 | _aNyce, Philip L | |
700 | 1 | _aVaz, Roy | |
700 | 1 | _aMetz, William A | |
773 | 0 |
_tJournal of medicinal chemistry _gvol. 48 _gno. 4 _gp. 995-1018 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm0491849 _zAvailable from publisher's website |
999 |
_c15391119 _d15391119 |