000 01994 a2200625 4500
005 20250514213645.0
264 0 _c20050217
008 200502s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm049485i
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aDoherty, Elizabeth M
245 0 0 _aDiscovery of potent, orally available vanilloid receptor-1 antagonists. Structure-activity relationship of N-aryl cinnamides.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cJan 2005
300 _a71-90 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAdministration, Oral
650 0 4 _aAnimals
650 0 4 _aBiochemistry
_xmethods
650 0 4 _aBiological Availability
650 0 4 _aCHO Cells
_xdrug effects
650 0 4 _aCalcium
_xmetabolism
650 0 4 _aCapsaicin
_xpharmacology
650 0 4 _aCinnamates
_xchemistry
650 0 4 _aCricetinae
650 0 4 _aCricetulus
650 0 4 _aHumans
650 0 4 _aHydrogen-Ion Concentration
650 0 4 _aInhibitory Concentration 50
650 0 4 _aIon Channels
_xantagonists & inhibitors
650 0 4 _aMale
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aRecombinant Proteins
_xdrug effects
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTRPV Cation Channels
700 1 _aFotsch, Christopher
700 1 _aBo, Yunxin
700 1 _aChakrabarti, Partha P
700 1 _aChen, Ning
700 1 _aGavva, Narender
700 1 _aHan, Nianhe
700 1 _aKelly, Michael G
700 1 _aKincaid, John
700 1 _aKlionsky, Lana
700 1 _aLiu, Qingyian
700 1 _aOgnyanov, Vassil I
700 1 _aTamir, Rami
700 1 _aWang, Xianghong
700 1 _aZhu, Jiawang
700 1 _aNorman, Mark H
700 1 _aTreanor, James J S
773 0 _tJournal of medicinal chemistry
_gvol. 48
_gno. 1
_gp. 71-90
856 4 0 _uhttps://doi.org/10.1021/jm049485i
_zAvailable from publisher's website
999 _c15314170
_d15314170