000 01694 a2200493 4500
005 20250514212710.0
264 0 _c20050628
008 200506s 0 0 eng d
022 _a0960-894X
024 7 _a10.1016/j.bmcl.2004.10.062
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLewis, Stephen J
245 0 0 _aA novel series of potent gamma-secretase inhibitors based on a benzobicyclo[4.2.1]nonane core.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_cJan 2005
300 _a373-8 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAlkanes
_xchemical synthesis
650 0 4 _aAlzheimer Disease
_xdrug therapy
650 0 4 _aAmides
_xchemistry
650 0 4 _aAmines
_xchemistry
650 0 4 _aAmyloid Precursor Protein Secretases
650 0 4 _aAnimals
650 0 4 _aAspartic Acid Endopeptidases
650 0 4 _aBrain
_xdrug effects
650 0 4 _aEndopeptidases
_xmetabolism
650 0 4 _aHeterocyclic Compounds
_xchemistry
650 0 4 _aMice
650 0 4 _aProtease Inhibitors
_xchemical synthesis
650 0 4 _aStructure-Activity Relationship
700 1 _aSmith, Adrian L
700 1 _aNeduvelil, Joseph G
700 1 _aStevenson, Graeme I
700 1 _aLindon, Matthew J
700 1 _aJones, A Brian
700 1 _aShearman, Mark S
700 1 _aBeher, Dirk
700 1 _aClarke, Earl
700 1 _aBest, Jonathan D
700 1 _aPeachey, James E
700 1 _aHarrison, Timothy
700 1 _aCastro, J Luis
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 15
_gno. 2
_gp. 373-8
856 4 0 _uhttps://doi.org/10.1016/j.bmcl.2004.10.062
_zAvailable from publisher's website
999 _c15286103
_d15286103