000 02570 a2200745 4500
005 20250514211842.0
264 0 _c20050628
008 200506s 0 0 eng d
022 _a0888-8809
024 7 _a10.1210/me.2004-0409
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aDenley, Adam
245 0 0 _aStructural and functional characteristics of the Val44Met insulin-like growth factor I missense mutation: correlation with effects on growth and development.
_h[electronic resource]
260 _bMolecular endocrinology (Baltimore, Md.)
_cMar 2005
300 _a711-21 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aBinding Sites
650 0 4 _aBinding, Competitive
650 0 4 _aBiological Assay
650 0 4 _aBlotting, Western
650 0 4 _aCell Proliferation
650 0 4 _aDNA
_xmetabolism
650 0 4 _aDNA Mutational Analysis
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aFibroblasts
_xmetabolism
650 0 4 _aHumans
650 0 4 _aImmunoprecipitation
650 0 4 _aInhibitory Concentration 50
650 0 4 _aInsulin
_xmetabolism
650 0 4 _aInsulin-Like Growth Factor I
_xgenetics
650 0 4 _aLigands
650 0 4 _aMagnetic Resonance Spectroscopy
650 0 4 _aMethionine
_xchemistry
650 0 4 _aMitogen-Activated Protein Kinase 1
_xmetabolism
650 0 4 _aMitogen-Activated Protein Kinase 3
_xmetabolism
650 0 4 _aModels, Molecular
650 0 4 _aMutation
650 0 4 _aMutation, Missense
650 0 4 _aPhenotype
650 0 4 _aPhosphorylation
650 0 4 _aPlasmids
_xmetabolism
650 0 4 _aProtein Binding
650 0 4 _aProtein Isoforms
650 0 4 _aProtein Serine-Threonine Kinases
_xmetabolism
650 0 4 _aProto-Oncogene Proteins
_xmetabolism
650 0 4 _aProto-Oncogene Proteins c-akt
650 0 4 _aReceptor, IGF Type 1
_xmetabolism
650 0 4 _aRecombinant Proteins
_xchemistry
650 0 4 _aSignal Transduction
650 0 4 _aSurface Plasmon Resonance
650 0 4 _aThymidine
_xchemistry
650 0 4 _aTime Factors
650 0 4 _aValine
_xchemistry
700 1 _aWang, Chunxiao C
700 1 _aMcNeil, Kerrie A
700 1 _aWalenkamp, Marie J E
700 1 _avan Duyvenvoorde, Hermine
700 1 _aWit, Jan M
700 1 _aWallace, John C
700 1 _aNorton, Raymond S
700 1 _aKarperien, Marcel
700 1 _aForbes, Briony E
773 0 _tMolecular endocrinology (Baltimore, Md.)
_gvol. 19
_gno. 3
_gp. 711-21
856 4 0 _uhttps://doi.org/10.1210/me.2004-0409
_zAvailable from publisher's website
999 _c15261595
_d15261595