000 01753 a2200529 4500
005 20250514210637.0
264 0 _c20050103
008 200501s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm040863t
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aChambers, Mark S
245 0 0 _aAn orally bioavailable, functionally selective inverse agonist at the benzodiazepine site of GABAA alpha5 receptors with cognition enhancing properties.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cNov 2004
300 _a5829-32 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAdministration, Oral
650 0 4 _aAnimals
650 0 4 _aBinding Sites
650 0 4 _aBiological Availability
650 0 4 _aCognition
_xdrug effects
650 0 4 _aDogs
650 0 4 _aGABA-A Receptor Agonists
650 0 4 _aIsoxazoles
_xadverse effects
650 0 4 _aMaze Learning
_xdrug effects
650 0 4 _aMice
650 0 4 _aNootropic Agents
_xadverse effects
650 0 4 _aPatch-Clamp Techniques
650 0 4 _aProtein Subunits
650 0 4 _aRadioligand Assay
650 0 4 _aRats
650 0 4 _aReceptors, GABA-A
_xmetabolism
650 0 4 _aTriazines
_xadverse effects
700 1 _aAtack, John R
700 1 _aCarling, Robert W
700 1 _aCollinson, Neil
700 1 _aCook, Susan M
700 1 _aDawson, Gerard R
700 1 _aFerris, Pushpindar
700 1 _aHobbs, Sarah C
700 1 _aO'connor, Desmond
700 1 _aMarshall, George
700 1 _aRycroft, W
700 1 _aMacleod, Angus M
773 0 _tJournal of medicinal chemistry
_gvol. 47
_gno. 24
_gp. 5829-32
856 4 0 _uhttps://doi.org/10.1021/jm040863t
_zAvailable from publisher's website
999 _c15224633
_d15224633