000 01412 a2200433 4500
005 20250514210310.0
264 0 _c20041217
008 200412s 0 0 eng d
022 _a1476-4687
024 7 _a10.1038/nature02993
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aThoma, Ralf
245 0 0 _aInsight into steroid scaffold formation from the structure of human oxidosqualene cyclase.
_h[electronic resource]
260 _bNature
_cNov 2004
300 _a118-22 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnticholesteremic Agents
_xchemistry
650 0 4 _aBenzophenones
_xchemistry
650 0 4 _aCatalysis
650 0 4 _aCrystallography, X-Ray
650 0 4 _aCyclization
650 0 4 _aDrug Design
650 0 4 _aHumans
650 0 4 _aIntramolecular Transferases
_xantagonists & inhibitors
650 0 4 _aLanosterol
_xchemistry
650 0 4 _aModels, Molecular
650 0 4 _aSqualene
_xanalogs & derivatives
650 0 4 _aStructure-Activity Relationship
700 1 _aSchulz-Gasch, Tanja
700 1 _aD'Arcy, Brigitte
700 1 _aBenz, Jörg
700 1 _aAebi, Johannes
700 1 _aDehmlow, Henrietta
700 1 _aHennig, Michael
700 1 _aStihle, Martine
700 1 _aRuf, Armin
773 0 _tNature
_gvol. 432
_gno. 7013
_gp. 118-22
856 4 0 _uhttps://doi.org/10.1038/nature02993
_zAvailable from publisher's website
999 _c15213851
_d15213851