000 01547 a2200385 4500
005 20250514203754.0
264 0 _c20050408
008 200504s 0 0 eng d
022 _a0090-9556
024 7 _a10.1124/dmd.104.001743
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHirani, Vandana N
245 0 0 _aConversion of the HIV protease inhibitor nelfinavir to a bioactive metabolite by human liver CYP2C19.
_h[electronic resource]
260 _bDrug metabolism and disposition: the biological fate of chemicals
_cDec 2004
300 _a1462-7 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAntibodies, Monoclonal
_xpharmacology
650 0 4 _aAryl Hydrocarbon Hydroxylases
_xantagonists & inhibitors
650 0 4 _aBiotransformation
650 0 4 _aCytochrome P-450 CYP2C19
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aHIV Protease Inhibitors
_xpharmacokinetics
650 0 4 _aHumans
650 0 4 _aHydroxylation
650 0 4 _aIn Vitro Techniques
650 0 4 _aKinetics
650 0 4 _aMicrosomes, Liver
_xmetabolism
650 0 4 _aMixed Function Oxygenases
_xantagonists & inhibitors
650 0 4 _aNelfinavir
_xanalogs & derivatives
650 0 4 _aOmeprazole
_xpharmacology
700 1 _aRaucy, Judy L
700 1 _aLasker, Jerome M
773 0 _tDrug metabolism and disposition: the biological fate of chemicals
_gvol. 32
_gno. 12
_gp. 1462-7
856 4 0 _uhttps://doi.org/10.1124/dmd.104.001743
_zAvailable from publisher's website
999 _c15140743
_d15140743