000 02022 a2200529 4500
005 20250514201736.0
264 0 _c20050207
008 200502s 0 0 eng d
022 _a0960-9822
024 7 _a10.1016/j.cub.2004.08.026
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aShah, O Jameel
245 0 0 _aInappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies.
_h[electronic resource]
260 _bCurrent biology : CB
_cSep 2004
300 _a1650-6 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aBlotting, Northern
650 0 4 _aCell Survival
_xphysiology
650 0 4 _aCells, Cultured
650 0 4 _aDown-Regulation
650 0 4 _aFlow Cytometry
650 0 4 _aHumans
650 0 4 _aImmunoblotting
650 0 4 _aImmunoprecipitation
650 0 4 _aInsulin Receptor Substrate Proteins
650 0 4 _aInsulin Resistance
_xphysiology
650 0 4 _aInsulin-Like Growth Factor I
_xmetabolism
650 0 4 _aMonomeric GTP-Binding Proteins
_xmetabolism
650 0 4 _aNeuropeptides
_xmetabolism
650 0 4 _aPhosphatidylinositol 3-Kinases
_xmetabolism
650 0 4 _aPhosphoproteins
_xmetabolism
650 0 4 _aProtein Kinases
_xmetabolism
650 0 4 _aProteins
_xmetabolism
650 0 4 _aRas Homolog Enriched in Brain Protein
650 0 4 _aRepressor Proteins
_xmetabolism
650 0 4 _aRibosomal Protein S6 Kinases
_xmetabolism
650 0 4 _aSignal Transduction
650 0 4 _aTOR Serine-Threonine Kinases
650 0 4 _aTuberous Sclerosis
_xmetabolism
650 0 4 _aTuberous Sclerosis Complex 1 Protein
650 0 4 _aTuberous Sclerosis Complex 2 Protein
650 0 4 _aTumor Suppressor Proteins
700 1 _aWang, Zhiyong
700 1 _aHunter, Tony
773 0 _tCurrent biology : CB
_gvol. 14
_gno. 18
_gp. 1650-6
856 4 0 _uhttps://doi.org/10.1016/j.cub.2004.08.026
_zAvailable from publisher's website
999 _c15073316
_d15073316