| 000 | 01811 a2200493 4500 | ||
|---|---|---|---|
| 005 | 20250514200551.0 | ||
| 264 | 0 | _c20041007 | |
| 008 | 200410s 0 0 eng d | ||
| 022 | _a0022-2623 | ||
| 024 | 7 |
_a10.1021/jm040058e _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aChen, Chen | |
| 245 | 0 | 0 |
_aDesign of 2,5-dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylaminopyrazolo[1,5-a]pyrimidine (NBI 30775/R121919) and structure--activity relationships of a series of potent and orally active corticotropin-releasing factor receptor antagonists. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cSep 2004 |
||
| 300 |
_a4787-98 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 |
_aAdrenocorticotropic Hormone _xmetabolism |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aCorticotropin-Releasing Hormone _xpharmacology |
| 650 | 0 | 4 |
_aCyclic AMP _xmetabolism |
| 650 | 0 | 4 | _aDrug Design |
| 650 | 0 | 4 | _aInhibitory Concentration 50 |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 | _aMolecular Structure |
| 650 | 0 | 4 |
_aPyrimidines _xadministration & dosage |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 | _aRats, Sprague-Dawley |
| 650 | 0 | 4 |
_aReceptors, Corticotropin-Releasing Hormone _xantagonists & inhibitors |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 700 | 1 | _aWilcoxen, Keith M | |
| 700 | 1 | _aHuang, Charles Q | |
| 700 | 1 | _aXie, Yun-Feng | |
| 700 | 1 | _aMcCarthy, James R | |
| 700 | 1 | _aWebb, Thomas R | |
| 700 | 1 | _aZhu, Yun-Fei | |
| 700 | 1 | _aSaunders, John | |
| 700 | 1 | _aLiu, Xin-Jun | |
| 700 | 1 | _aChen, Ta-Kung | |
| 700 | 1 | _aBozigian, Haig | |
| 700 | 1 | _aGrigoriadis, Dimitri E | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 47 _gno. 19 _gp. 4787-98 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm040058e _zAvailable from publisher's website |
| 999 |
_c15038566 _d15038566 |
||