000 01349 a2200397 4500
005 20250511190130.0
264 0 _c19920904
008 199209s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm00093a007
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWarner, P
245 0 0 _aQuinoline antifolate thymidylate synthase inhibitors: variation of the C2- and C4-substituents.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cJul 1992
300 _a2761-8 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnimals
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aFolic Acid
_xanalogs & derivatives
650 0 4 _aFolic Acid Antagonists
_xchemistry
650 0 4 _aLeukemia L1210
_xenzymology
650 0 4 _aMice
650 0 4 _aQuinazolines
_xchemistry
650 0 4 _aStructure-Activity Relationship
650 0 4 _aThymidylate Synthase
_xantagonists & inhibitors
650 0 4 _aTumor Cells, Cultured
700 1 _aBarker, A J
700 1 _aJackman, A L
700 1 _aBurrows, K D
700 1 _aRoberts, N
700 1 _aBishop, J A
700 1 _aO'Connor, B M
700 1 _aHughes, L R
773 0 _tJournal of medicinal chemistry
_gvol. 35
_gno. 15
_gp. 2761-8
856 4 0 _uhttps://doi.org/10.1021/jm00093a007
_zAvailable from publisher's website
999 _c1501495
_d1501495