000 01985 a2200529 4500
005 20250514195049.0
264 0 _c20040830
008 200408s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm0499108
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSun, Haiying
245 0 0 _aStructure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondria-derived activator of caspase that target the X-linked inhibitor of apoptosis protein/caspase-9 interaction site.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cAug 2004
300 _a4147-50 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAmino Acid Motifs
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aApoptosis Regulatory Proteins
650 0 4 _aCarrier Proteins
_xchemistry
650 0 4 _aCaspase 9
650 0 4 _aCaspases
_xmetabolism
650 0 4 _aCell Line, Tumor
650 0 4 _aCyclization
650 0 4 _aHeterocyclic Compounds, 2-Ring
_xchemical synthesis
650 0 4 _aHumans
650 0 4 _aIntracellular Signaling Peptides and Proteins
650 0 4 _aMitochondrial Proteins
_xchemistry
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Conformation
650 0 4 _aMolecular Mimicry
650 0 4 _aOligopeptides
_xchemistry
650 0 4 _aProtein Binding
650 0 4 _aProtein Structure, Tertiary
650 0 4 _aProteins
_xmetabolism
650 0 4 _aStructure-Activity Relationship
650 0 4 _aX-Linked Inhibitor of Apoptosis Protein
700 1 _aNikolovska-Coleska, Zaneta
700 1 _aYang, Chao-Yie
700 1 _aXu, Liang
700 1 _aTomita, York
700 1 _aKrajewski, Krzysztof
700 1 _aRoller, Peter P
700 1 _aWang, Shaomeng
773 0 _tJournal of medicinal chemistry
_gvol. 47
_gno. 17
_gp. 4147-50
856 4 0 _uhttps://doi.org/10.1021/jm0499108
_zAvailable from publisher's website
999 _c14994415
_d14994415