000 02590 a2200757 4500
005 20250514194754.0
264 0 _c20041124
008 200411s 0 0 eng d
022 _a0021-9258
024 7 _a10.1074/jbc.M406051200
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aChiara, Federica
245 0 0 _aA gain of function mutation in the activation loop of platelet-derived growth factor beta-receptor deregulates its kinase activity.
_h[electronic resource]
260 _bThe Journal of biological chemistry
_cOct 2004
300 _a42516-27 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aActins
_xmetabolism
650 0 4 _aAnimals
650 0 4 _aApoptosis
650 0 4 _aAsparagine
_xchemistry
650 0 4 _aAspartic Acid
_xchemistry
650 0 4 _aBecaplermin
650 0 4 _aBinding Sites
650 0 4 _aCOS Cells
650 0 4 _aCells, Cultured
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aEnzyme Activation
650 0 4 _aFibroblasts
_xmetabolism
650 0 4 _aFlow Cytometry
650 0 4 _aGenetic Vectors
650 0 4 _aHumans
650 0 4 _aKinetics
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMice, Mutant Strains
650 0 4 _aMitogen-Activated Protein Kinase 1
_xmetabolism
650 0 4 _aMitogen-Activated Protein Kinase 3
_xmetabolism
650 0 4 _aMutation
650 0 4 _aNIH 3T3 Cells
650 0 4 _aPhosphatidylinositol 3-Kinases
_xmetabolism
650 0 4 _aPlatelet-Derived Growth Factor
_xmetabolism
650 0 4 _aPoint Mutation
650 0 4 _aProtein Serine-Threonine Kinases
_xmetabolism
650 0 4 _aProtein Structure, Tertiary
650 0 4 _aProto-Oncogene Proteins
_xmetabolism
650 0 4 _aProto-Oncogene Proteins c-akt
650 0 4 _aProto-Oncogene Proteins c-sis
650 0 4 _aReceptor, Platelet-Derived Growth Factor beta
_xgenetics
650 0 4 _aSignal Transduction
650 0 4 _aSubstrate Specificity
650 0 4 _aTime Factors
650 0 4 _aTyrosine
_xchemistry
650 0 4 _aUp-Regulation
650 0 4 _aWound Healing
700 1 _aGoumans, Marie-José
700 1 _aForsberg, Henrik
700 1 _aAhgrén, Aive
700 1 _aRasola, Andrea
700 1 _aAspenström, Pontus
700 1 _aWernstedt, Christer
700 1 _aHellberg, Carina
700 1 _aHeldin, Carl-Henrik
700 1 _aHeuchel, Rainer
773 0 _tThe Journal of biological chemistry
_gvol. 279
_gno. 41
_gp. 42516-27
856 4 0 _uhttps://doi.org/10.1074/jbc.M406051200
_zAvailable from publisher's website
999 _c14985561
_d14985561