000 02119 a2200541 4500
005 20250514192703.0
264 0 _c20040916
008 200409s 0 0 eng d
022 _a0012-1797
024 7 _a10.2337/diabetes.53.7.1706
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMaedler, Kathrin
245 0 0 _aGlucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets.
_h[electronic resource]
260 _bDiabetes
_cJul 2004
300 _a1706-13 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aATP-Binding Cassette Transporters
650 0 4 _aAged
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBridged Bicyclo Compounds, Heterocyclic
_xpharmacology
650 0 4 _aCalcium
_xmetabolism
650 0 4 _aCalcium Channels, L-Type
_xmetabolism
650 0 4 _aCells, Cultured
650 0 4 _aCyclic S-Oxides
_xpharmacology
650 0 4 _aDiazoxide
_xpharmacology
650 0 4 _aDrug Synergism
650 0 4 _aEnzyme Activation
_xphysiology
650 0 4 _aGlucose
_xpharmacology
650 0 4 _aHumans
650 0 4 _aInterleukin-1
_xpharmacology
650 0 4 _aIslets of Langerhans
_xdrug effects
650 0 4 _aMiddle Aged
650 0 4 _aMitogen-Activated Protein Kinases
_xmetabolism
650 0 4 _aPotassium Channels
_xdrug effects
650 0 4 _aPotassium Channels, Inwardly Rectifying
_xdrug effects
650 0 4 _aReceptors, Drug
650 0 4 _aSulfonylurea Receptors
650 0 4 _aTolbutamide
_xpharmacology
700 1 _aStørling, Joachim
700 1 _aSturis, Jeppe
700 1 _aZuellig, Richard A
700 1 _aSpinas, Giatgen A
700 1 _aArkhammar, Per O G
700 1 _aMandrup-Poulsen, Thomas
700 1 _aDonath, Marc Y
773 0 _tDiabetes
_gvol. 53
_gno. 7
_gp. 1706-13
856 4 0 _uhttps://doi.org/10.2337/diabetes.53.7.1706
_zAvailable from publisher's website
999 _c14925222
_d14925222