000			02185 a2200661 4500
005			20250514192522.0
264		0	_c20040802
008			200408s 0 0 eng d
022			_a0022-2623
024	7		_a10.1021/jm0407613 _2doi
040			_aNLM _beng _cNLM
100	1		_aStreet, Leslie J
245	0	0	_aSynthesis and biological evaluation of 3-heterocyclyl-7,8,9,10-tetrahydro-(7,10-ethano)-1,2,4-triazolo[3,4-a]phthalazines and analogues as subtype-selective inverse agonists for the GABA(A)alpha5 benzodiazepine binding site. _h[electronic resource]
260			_bJournal of medicinal chemistry _cJul 2004
300			_a3642-57 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAdministration, Oral
650	0	4	_aAnimals
650	0	4	_aBinding Sites
650	0	4	_aBiological Availability
650	0	4	_aCell Line
650	0	4	_aFemale
650	0	4	_aGABA-A Receptor Agonists
650	0	4	_aHumans
650	0	4	_aIsoxazoles _xchemical synthesis
650	0	4	_aMale
650	0	4	_aMaze Learning _xdrug effects
650	0	4	_aOocytes _xdrug effects
650	0	4	_aPatch-Clamp Techniques
650	0	4	_aPhthalazines _xchemical synthesis
650	0	4	_aProtein Subunits _xagonists
650	0	4	_aRadioligand Assay
650	0	4	_aRats
650	0	4	_aStructure-Activity Relationship
650	0	4	_aTriazoles _xchemical synthesis
650	0	4	_aXenopus laevis
700	1		_aSternfeld, Francine
700	1		_aJelley, Richard A
700	1		_aReeve, Austin J
700	1		_aCarling, Robert W
700	1		_aMoore, Kevin W
700	1		_aMcKernan, Ruth M
700	1		_aSohal, Bindi
700	1		_aCook, Susan
700	1		_aPike, Andrew
700	1		_aDawson, Gerard R
700	1		_aBromidge, Frances A
700	1		_aWafford, Keith A
700	1		_aSeabrook, Guy R
700	1		_aThompson, Sally A
700	1		_aMarshall, George
700	1		_aPillai, Goplan V
700	1		_aCastro, José L
700	1		_aAtack, John R
700	1		_aMacLeod, Angus M
773	0		_tJournal of medicinal chemistry _gvol. 47 _gno. 14 _gp. 3642-57
856	4	0	_uhttps://doi.org/10.1021/jm0407613 _zAvailable from publisher's website
999			_c14920025 _d14920025