000 02004 a2200553 4500
005 20250514165626.0
264 0 _c20040401
008 200404s 0 0 eng d
022 _a0008-5472
024 7 _a10.1158/0008-5472.can-3554-2
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBoulay, Anne
245 0 0 _aAntitumor efficacy of intermittent treatment schedules with the rapamycin derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in peripheral blood mononuclear cells.
_h[electronic resource]
260 _bCancer research
_cJan 2004
300 _a252-61 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aDisease Models, Animal
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Administration Schedule
650 0 4 _aDrug Monitoring
_xmethods
650 0 4 _aEverolimus
650 0 4 _aHumans
650 0 4 _aImmunosuppressive Agents
_xadministration & dosage
650 0 4 _aLeukocytes, Mononuclear
_xenzymology
650 0 4 _aMAP Kinase Signaling System
_xdrug effects
650 0 4 _aMale
650 0 4 _aPancreatic Neoplasms
_xdrug therapy
650 0 4 _aRats
650 0 4 _aRats, Inbred Lew
650 0 4 _aRibosomal Protein S6 Kinases, 90-kDa
_xantagonists & inhibitors
650 0 4 _aSirolimus
_xadministration & dosage
650 0 4 _aTime Factors
650 0 4 _aTumor Cells, Cultured
700 1 _aZumstein-Mecker, Sabine
700 1 _aStephan, Christine
700 1 _aBeuvink, Iwan
700 1 _aZilbermann, Frederic
700 1 _aHaller, Roland
700 1 _aTobler, Sonja
700 1 _aHeusser, Christoph
700 1 _aO'Reilly, Terence
700 1 _aStolz, Barbara
700 1 _aMarti, Andreas
700 1 _aThomas, George
700 1 _aLane, Heidi A
773 0 _tCancer research
_gvol. 64
_gno. 1
_gp. 252-61
856 4 0 _uhttps://doi.org/10.1158/0008-5472.can-3554-2
_zAvailable from publisher's website
999 _c14455981
_d14455981