000 02370 a2200685 4500
005 20250514165354.0
264 0 _c20040920
008 200409s 0 0 eng d
022 _a1431-6730
024 7 _a10.1515/BC.2003.171
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aGreen, Brian D
245 0 0 _aMetabolic stability, receptor binding, cAMP generation, insulin secretion and antihyperglycaemic activity of novel N-terminal Glu9-substituted analogues of glucagon-like peptide-1.
_h[electronic resource]
260 _bBiological chemistry
_cDec 2003
300 _a1543-51 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdenosine Deaminase
_xmetabolism
650 0 4 _aAmino Acid Substitution
650 0 4 _aAnimals
650 0 4 _aBinding, Competitive
650 0 4 _aBlood Glucose
_xdrug effects
650 0 4 _aCell Line, Tumor
650 0 4 _aCricetinae
650 0 4 _aCyclic AMP
_xmetabolism
650 0 4 _aDiabetes Mellitus, Type 2
_xdrug therapy
650 0 4 _aDipeptidyl Peptidase 4
650 0 4 _aFibroblasts
_xmetabolism
650 0 4 _aGlucagon
_xgenetics
650 0 4 _aGlucagon-Like Peptide 1
650 0 4 _aGlucagon-Like Peptide-1 Receptor
650 0 4 _aGlucose
_xpharmacology
650 0 4 _aGlutamine
_xchemistry
650 0 4 _aGlycoproteins
_xmetabolism
650 0 4 _aHumans
650 0 4 _aHypoglycemic Agents
_xmetabolism
650 0 4 _aInsulin
_xblood
650 0 4 _aInsulin Secretion
650 0 4 _aIslets of Langerhans
_xdrug effects
650 0 4 _aMice
650 0 4 _aMice, Obese
650 0 4 _aPeptide Fragments
_xgenetics
650 0 4 _aPhenylalanine
_xchemistry
650 0 4 _aProline
_xchemistry
650 0 4 _aProtein Precursors
_xgenetics
650 0 4 _aRats
650 0 4 _aReceptors, Glucagon
_xmetabolism
650 0 4 _aSpectrometry, Mass, Electrospray Ionization
650 0 4 _aTransformation, Genetic
650 0 4 _aTyrosine
_xchemistry
700 1 _aGault, Victor A
700 1 _aIrwin, Nigel
700 1 _aMooney, Mark H
700 1 _aBailey, Clifford J
700 1 _aHarriott, Patrick
700 1 _aGreer, Brett
700 1 _aFlatt, Peter R
700 1 _aO'Harte, Finbarr P M
773 0 _tBiological chemistry
_gvol. 384
_gno. 12
_gp. 1543-51
856 4 0 _uhttps://doi.org/10.1515/BC.2003.171
_zAvailable from publisher's website
999 _c14447976
_d14447976