000 | 02480 a2200673 4500 | ||
---|---|---|---|
005 | 20250514165050.0 | ||
264 | 0 | _c20040913 | |
008 | 200409s 0 0 eng d | ||
022 | _a0090-9556 | ||
024 | 7 |
_a10.1124/dmd.32.1.149 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aKoyano, Satoru | |
245 | 0 | 0 |
_aFunctional characterization of four naturally occurring variants of human pregnane X receptor (PXR): one variant causes dramatic loss of both DNA binding activity and the transactivation of the CYP3A4 promoter/enhancer region. _h[electronic resource] |
260 |
_bDrug metabolism and disposition: the biological fate of chemicals _cJan 2004 |
||
300 |
_a149-54 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 | _aAmino Acid Sequence |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aBiotransformation _xdrug effects |
650 | 0 | 4 | _aBlotting, Western |
650 | 0 | 4 | _aCOS Cells |
650 | 0 | 4 | _aCell Line, Tumor |
650 | 0 | 4 | _aChlorocebus aethiops |
650 | 0 | 4 |
_aClotrimazole _xpharmacology |
650 | 0 | 4 | _aCytochrome P-450 CYP3A |
650 | 0 | 4 |
_aCytochrome P-450 Enzyme System _xgenetics |
650 | 0 | 4 |
_aDNA _xgenetics |
650 | 0 | 4 | _aElectrophoretic Mobility Shift Assay |
650 | 0 | 4 |
_aEnhancer Elements, Genetic _xgenetics |
650 | 0 | 4 |
_aExons _xgenetics |
650 | 0 | 4 |
_aGenes, Reporter _xgenetics |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aImmunohistochemistry |
650 | 0 | 4 |
_aLuciferases _xgenetics |
650 | 0 | 4 | _aMolecular Sequence Data |
650 | 0 | 4 |
_aPaclitaxel _xpharmacology |
650 | 0 | 4 |
_aPlasmids _xgenetics |
650 | 0 | 4 | _aPregnane X Receptor |
650 | 0 | 4 |
_aPromoter Regions, Genetic _xgenetics |
650 | 0 | 4 |
_aReceptors, Cytoplasmic and Nuclear _xgenetics |
650 | 0 | 4 |
_aReceptors, Steroid _xgenetics |
650 | 0 | 4 |
_aRifampin _xpharmacology |
650 | 0 | 4 |
_aTranscriptional Activation _xgenetics |
700 | 1 | _aKurose, Kouichi | |
700 | 1 | _aSaito, Yoshiro | |
700 | 1 | _aOzawa, Shogo | |
700 | 1 | _aHasegawa, Ryuichi | |
700 | 1 | _aKomamura, Kazuo | |
700 | 1 | _aUeno, Kazuyuki | |
700 | 1 | _aKamakura, Shiro | |
700 | 1 | _aKitakaze, Masafumi | |
700 | 1 | _aNakajima, Toshiharu | |
700 | 1 | _aMatsumoto, Kenji | |
700 | 1 | _aAkasawa, Akira | |
700 | 1 | _aSaito, Hirohisa | |
700 | 1 | _aSawada, Jun-Ichi | |
773 | 0 |
_tDrug metabolism and disposition: the biological fate of chemicals _gvol. 32 _gno. 1 _gp. 149-54 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1124/dmd.32.1.149 _zAvailable from publisher's website |
999 |
_c14438663 _d14438663 |