000 02535 a2200793 4500
005 20250514163618.0
264 0 _c20040211
008 200402s 0 0 eng d
022 _a1526-632X
024 7 _a10.1212/01.wnl.0000095219.22086.31
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKase, Hiroshi
245 0 0 _aProgress in pursuit of therapeutic A2A antagonists: the adenosine A2A receptor selective antagonist KW6002: research and development toward a novel nondopaminergic therapy for Parkinson's disease.
_h[electronic resource]
260 _bNeurology
_cDec 2003
300 _aS97-100 p.
_bdigital
500 _aPublication Type: Journal Article; Review
650 0 4 _aAdenosine A2 Receptor Antagonists
650 0 4 _aAnimals
650 0 4 _aAntiparkinson Agents
_xadverse effects
650 0 4 _aClinical Trials as Topic
_xstatistics & numerical data
650 0 4 _aCorpus Striatum
_xcytology
650 0 4 _aDisease Models, Animal
650 0 4 _aDrug Evaluation, Preclinical
650 0 4 _aDyskinesia, Drug-Induced
_xprevention & control
650 0 4 _aGlobus Pallidus
_xcytology
650 0 4 _aHumans
650 0 4 _aLevodopa
_xadverse effects
650 0 4 _aMice
650 0 4 _aMice, Knockout
650 0 4 _aMotor Activity
_xdrug effects
650 0 4 _aNeurons
_xdrug effects
650 0 4 _aOxidopamine
650 0 4 _aParkinson Disease
_xdrug therapy
650 0 4 _aParkinsonian Disorders
_xchemically induced
650 0 4 _aPrimates
650 0 4 _aPurines
_xtherapeutic use
650 0 4 _aRats
650 0 4 _aReceptor, Adenosine A2A
_xmetabolism
650 0 4 _aReceptors, Dopamine D2
_xdeficiency
650 0 4 _agamma-Aminobutyric Acid
_xmetabolism
700 1 _aAoyama, S
700 1 _aIchimura, M
700 1 _aIkeda, K
700 1 _aIshii, A
700 1 _aKanda, T
700 1 _aKoga, K
700 1 _aKoike, N
700 1 _aKurokawa, M
700 1 _aKuwana, Y
700 1 _aMori, A
700 1 _aNakamura, J
700 1 _aNonaka, H
700 1 _aOchi, M
700 1 _aSaki, M
700 1 _aShimada, J
700 1 _aShindou, T
700 1 _aShiozaki, S
700 1 _aSuzuki, F
700 1 _aTakeda, M
700 1 _aYanagawa, K
700 1 _aRichardson, P J
700 1 _aJenner, P
700 1 _aBedard, P
700 1 _aBorrelli, E
700 1 _aHauser, R A
700 1 _aChase, T N
773 0 _tNeurology
_gvol. 61
_gno. 11 Suppl 6
_gp. S97-100
856 4 0 _uhttps://doi.org/10.1212/01.wnl.0000095219.22086.31
_zAvailable from publisher's website
999 _c14396570
_d14396570