000			02172 a2200613 4500
005			20250514163208.0
264		0	_c20040123
008			200401s 0 0 eng d
022			_a0020-7136
024	7		_a10.1002/ijc.11539 _2doi
040			_aNLM _beng _cNLM
100	1		_aKoizumi, Fumiaki
245	0	0	_aSynergistic interaction between the EGFR tyrosine kinase inhibitor gefitinib ("Iressa") and the DNA topoisomerase I inhibitor CPT-11 (irinotecan) in human colorectal cancer cells. _h[electronic resource]
260			_bInternational journal of cancer _cJan 2004
300			_a464-72 p. _bdigital
500			_aPublication Type: Comparative Study; Journal Article
650	0	4	_aAnimals
650	0	4	_aApoptosis _xdrug effects
650	0	4	_aCamptothecin _xanalogs & derivatives
650	0	4	_aCell Division _xdrug effects
650	0	4	_aColorectal Neoplasms _xdrug therapy
650	0	4	_aDNA Topoisomerases, Type I _xgenetics
650	0	4	_aDrug Interactions
650	0	4	_aDrug Synergism
650	0	4	_aDrug Therapy, Combination
650	0	4	_aEnzyme Inhibitors _xtherapeutic use
650	0	4	_aErbB Receptors _xantagonists & inhibitors
650	0	4	_aFemale
650	0	4	_aGefitinib
650	0	4	_aHumans
650	0	4	_aIrinotecan
650	0	4	_aMice
650	0	4	_aMice, Inbred BALB C
650	0	4	_aMice, Nude
650	0	4	_aPhosphorylation
650	0	4	_aPoly(ADP-ribose) Polymerases _xmetabolism
650	0	4	_aQuinazolines _xtherapeutic use
650	0	4	_aRNA, Messenger _xmetabolism
650	0	4	_aReceptor, ErbB-2 _xmetabolism
650	0	4	_aReverse Transcriptase Polymerase Chain Reaction
650	0	4	_aTopoisomerase I Inhibitors
650	0	4	_aTumor Cells, Cultured
650	0	4	_aXenograft Model Antitumor Assays
700	1		_aKanzawa, Fumihiko
700	1		_aUeda, Yutaka
700	1		_aKoh, Yasuhiro
700	1		_aTsukiyama, Shoji
700	1		_aTaguchi, Fumiko
700	1		_aTamura, Tomohide
700	1		_aSaijo, Nagahiro
700	1		_aNishio, Kazuto
773	0		_tInternational journal of cancer _gvol. 108 _gno. 3 _gp. 464-72
856	4	0	_uhttps://doi.org/10.1002/ijc.11539 _zAvailable from publisher's website
999			_c14383137 _d14383137