000 02084 a2200541 4500
005 20250514155522.0
264 0 _c20031216
008 200312s 0 0 eng d
022 _a0360-4012
024 7 _a10.1002/jnr.10756
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHuang, Hsueh-Meei
245 0 0 _aInhibition of alpha-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, and necrotic cell death.
_h[electronic resource]
260 _bJournal of neuroscience research
_cOct 2003
300 _a309-17 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAnimals
650 0 4 _aCaspase 3
650 0 4 _aCaspases
_xmetabolism
650 0 4 _aCell Death
_xdrug effects
650 0 4 _aCell Membrane Permeability
_xdrug effects
650 0 4 _aChromatin
_xdrug effects
650 0 4 _aCyclosporine
_xpharmacology
650 0 4 _aCytochromes c
_xmetabolism
650 0 4 _aIon Channels
_xantagonists & inhibitors
650 0 4 _aKeto Acids
_xpharmacology
650 0 4 _aKetoglutarate Dehydrogenase Complex
_xantagonists & inhibitors
650 0 4 _aL-Lactate Dehydrogenase
_xmetabolism
650 0 4 _aMatrix Metalloproteinases
_xdrug effects
650 0 4 _aMembrane Potentials
_xdrug effects
650 0 4 _aMitochondria
_xdrug effects
650 0 4 _aMitochondrial Membrane Transport Proteins
650 0 4 _aMitochondrial Permeability Transition Pore
650 0 4 _aNecrosis
650 0 4 _aNeurodegenerative Diseases
_xenzymology
650 0 4 _aNeurons
_xdrug effects
650 0 4 _aPC12 Cells
650 0 4 _aProtein Transport
_xdrug effects
650 0 4 _aRats
650 0 4 _aReactive Oxygen Species
_xmetabolism
700 1 _aOu, Hsiu-Chong
700 1 _aXu, Hui
700 1 _aChen, Huan-Lian
700 1 _aFowler, Corinne
700 1 _aGibson, Gary E
773 0 _tJournal of neuroscience research
_gvol. 74
_gno. 2
_gp. 309-17
856 4 0 _uhttps://doi.org/10.1002/jnr.10756
_zAvailable from publisher's website
999 _c14275932
_d14275932