| 000 | 01591 a2200433 4500 | ||
|---|---|---|---|
| 005 | 20250511180934.0 | ||
| 264 | 0 | _c19940317 | |
| 008 | 199403s 0 0 eng d | ||
| 022 | _a1059-2725 | ||
| 040 |
_aNLM _beng _cNLM |
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| 100 | 1 | _aGoodkin, D E | |
| 245 | 0 | 0 |
_aLow-dose (7.5 mg) oral methotrexate for chronic progressive multiple sclerosis. Design of a randomized, placebo-controlled trial with sample size benefits from a composite outcome variable including preliminary data on toxicity. _h[electronic resource] |
| 260 |
_bThe Online journal of current clinical trials _cSep 1992 |
||
| 300 |
_a[7723 words; 89 paragraphs] p. _bdigital |
||
| 500 | _aPublication Type: Clinical Trial; Journal Article; Randomized Controlled Trial | ||
| 650 | 0 | 4 | _aAdult |
| 650 | 0 | 4 |
_aCentral Nervous System _xdrug effects |
| 650 | 0 | 4 | _aChronic Disease |
| 650 | 0 | 4 | _aDouble-Blind Method |
| 650 | 0 | 4 | _aDrug Administration Schedule |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 |
_aMethotrexate _xadministration & dosage |
| 650 | 0 | 4 | _aMiddle Aged |
| 650 | 0 | 4 |
_aMultiple Sclerosis _xdrug therapy |
| 650 | 0 | 4 | _aNeuropsychological Tests |
| 650 | 0 | 4 | _aOutcome Assessment, Health Care |
| 650 | 0 | 4 | _aResearch Design |
| 700 | 1 | _aRudick, R A | |
| 700 | 1 | _aVanderBrug Medendorp, S | |
| 700 | 1 | _aGreene, T | |
| 700 | 1 | _aSchwetz, K M | |
| 700 | 1 | _aFischer, J | |
| 700 | 1 | _aDaughtry, M M | |
| 700 | 1 | _aRoss, J | |
| 700 | 1 | _aVan Dyke, C | |
| 773 | 0 |
_tThe Online journal of current clinical trials _gvol. Doc No 19 _gp. [7723 words; 89 paragraphs] |
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| 999 |
_c1350132 _d1350132 |
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