000			02086 a2200589 4500
005			20250514080356.0
264		0	_c20040112
008			200401s 0 0 eng d
022			_a0021-9258
024	7		_a10.1074/jbc.M308480200 _2doi
040			_aNLM _beng _cNLM
100	1		_aLleó, Alberto
245	0	0	_aNotch1 competes with the amyloid precursor protein for gamma-secretase and down-regulates presenilin-1 gene expression. _h[electronic resource]
260			_bThe Journal of biological chemistry _cNov 2003
300			_a47370-5 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650	0	4	_aAmyloid Precursor Protein Secretases
650	0	4	_aAmyloid beta-Protein Precursor _xmetabolism
650	0	4	_aAnimals
650	0	4	_aAspartic Acid Endopeptidases
650	0	4	_aBinding, Competitive
650	0	4	_aBlotting, Western
650	0	4	_aCell Line
650	0	4	_aCell Line, Tumor
650	0	4	_aDown-Regulation
650	0	4	_aEndopeptidases _xmetabolism
650	0	4	_aEnzyme-Linked Immunosorbent Assay
650	0	4	_aFeedback, Physiological
650	0	4	_aHumans
650	0	4	_aLuciferases _xmetabolism
650	0	4	_aMembrane Proteins _xbiosynthesis
650	0	4	_aMice
650	0	4	_aPlasmids _xmetabolism
650	0	4	_aPresenilin-1
650	0	4	_aProtein Binding
650	0	4	_aProtein Structure, Tertiary
650	0	4	_aReceptor, Notch1
650	0	4	_aReceptors, Cell Surface _xgenetics
650	0	4	_aReverse Transcriptase Polymerase Chain Reaction
650	0	4	_aSignal Transduction
650	0	4	_aTranscription Factors
650	0	4	_aTransfection
650	0	4	_abeta-Galactosidase _xmetabolism
700	1		_aBerezovska, Oksana
700	1		_aRamdya, Pavan
700	1		_aFukumoto, Hiroaki
700	1		_aRaju, Susan
700	1		_aShah, Tejal
700	1		_aHyman, Bradley T
773	0		_tThe Journal of biological chemistry _gvol. 278 _gno. 48 _gp. 47370-5
856	4	0	_uhttps://doi.org/10.1074/jbc.M308480200 _zAvailable from publisher's website
999			_c12729170 _d12729170