| 000 | 01874 a2200517 4500 | ||
|---|---|---|---|
| 005 | 20250514080207.0 | ||
| 264 | 0 | _c20031110 | |
| 008 | 200311s 0 0 eng d | ||
| 022 | _a0022-2623 | ||
| 024 | 7 |
_a10.1021/jm034134+ _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aWatanabe, Nobuhide | |
| 245 | 0 | 0 |
_aDiscovery and preclinical characterization of (+)-3-[4-(1- piperidinoethoxy)phenyl]spiro[indene- 1,1'-indane]-5,5'-diol hydrochloride: a promising nonsteroidal estrogen receptor agonist for hot flush. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cSep 2003 |
||
| 300 |
_a3961-4 p. _bdigital |
||
| 500 | _aPublication Type: Comparative Study; Journal Article | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aBone Density _xdrug effects |
| 650 | 0 | 4 |
_aBreast Neoplasms _xmetabolism |
| 650 | 0 | 4 |
_aCholesterol _xblood |
| 650 | 0 | 4 | _aDrug Evaluation, Preclinical |
| 650 | 0 | 4 |
_aEstradiol _xanalogs & derivatives |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 |
_aHot Flashes _xdrug therapy |
| 650 | 0 | 4 |
_aIndans _xchemistry |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 |
_aMorphine Dependence _xmetabolism |
| 650 | 0 | 4 |
_aNaloxone _xpharmacology |
| 650 | 0 | 4 |
_aPiperidines _xchemistry |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 | _aRats, Sprague-Dawley |
| 650 | 0 | 4 |
_aReceptors, Estrogen _xagonists |
| 650 | 0 | 4 |
_aSelective Estrogen Receptor Modulators _xchemistry |
| 650 | 0 | 4 |
_aSkin Temperature _xdrug effects |
| 650 | 0 | 4 |
_aSpiro Compounds _xchemistry |
| 650 | 0 | 4 | _aStereoisomerism |
| 650 | 0 | 4 | _aTumor Cells, Cultured |
| 650 | 0 | 4 |
_aUterus _xdrug effects |
| 700 | 1 | _aIkeno, Akihisa | |
| 700 | 1 | _aMinato, Hisao | |
| 700 | 1 | _aNakagawa, Hiroshi | |
| 700 | 1 | _aKohayakawa, Chie | |
| 700 | 1 | _aTsuji, Jun-ichi | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 46 _gno. 19 _gp. 3961-4 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm034134+ _zAvailable from publisher's website |
| 999 |
_c12723437 _d12723437 |
||