000 02493 a2200661 4500
005 20250514071656.0
264 0 _c20030822
008 200308s 0 0 eng d
022 _a0143-3334
024 7 _a10.1093/carcin/bgg082
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWoo, Ju-Hyung
245 0 0 _aMolecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt.
_h[electronic resource]
260 _bCarcinogenesis
_cJul 2003
300 _a1199-208 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBlotting, Western
650 0 4 _aCarcinoma, Renal Cell
_xmetabolism
650 0 4 _aCaspases
_xmetabolism
650 0 4 _aCurcumin
_xpharmacology
650 0 4 _aCytochrome c Group
_xmetabolism
650 0 4 _aDown-Regulation
650 0 4 _aEnzyme Activation
_xdrug effects
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aFree Radical Scavengers
_xpharmacology
650 0 4 _aGene Expression Regulation, Neoplastic
650 0 4 _aHumans
650 0 4 _aInhibitor of Apoptosis Proteins
650 0 4 _aKidney Neoplasms
_xmetabolism
650 0 4 _aMitochondria
_xdrug effects
650 0 4 _aPoly(ADP-ribose) Polymerases
_xmetabolism
650 0 4 _aProtein Serine-Threonine Kinases
650 0 4 _aProteins
_xantagonists & inhibitors
650 0 4 _aProto-Oncogene Proteins
_xantagonists & inhibitors
650 0 4 _aProto-Oncogene Proteins c-akt
650 0 4 _aProto-Oncogene Proteins c-bcl-2
_xantagonists & inhibitors
650 0 4 _aRNA, Messenger
_xmetabolism
650 0 4 _aReactive Oxygen Species
650 0 4 _aReverse Transcriptase Polymerase Chain Reaction
650 0 4 _aTumor Cells, Cultured
650 0 4 _abcl-2-Associated X Protein
650 0 4 _abcl-X Protein
700 1 _aKim, Young-Ho
700 1 _aChoi, Yun-Jung
700 1 _aKim, Dae-Gon
700 1 _aLee, Kyung-Seop
700 1 _aBae, Jae Hoon
700 1 _aMin, Do Sik
700 1 _aChang, Jong-Soo
700 1 _aJeong, Yong-Jin
700 1 _aLee, Young Han
700 1 _aPark, Jong-Wook
700 1 _aKwon, Taeg Kyu
773 0 _tCarcinogenesis
_gvol. 24
_gno. 7
_gp. 1199-208
856 4 0 _uhttps://doi.org/10.1093/carcin/bgg082
_zAvailable from publisher's website
999 _c12591843
_d12591843