000			01950 a2200577 4500
005			20250514070602.0
264		0	_c20030711
008			200307s 0 0 eng d
022			_a0022-2623
024	7		_a10.1021/jm0205548 _2doi
040			_aNLM _beng _cNLM
100	1		_aAranapakam, Venkatesan
245	0	0	_aSynthesis and structure-activity relationship of alpha-sulfonylhydroxamic acids as novel, orally active matrix metalloproteinase inhibitors for the treatment of osteoarthritis. _h[electronic resource]
260			_bJournal of medicinal chemistry _cJun 2003
300			_a2361-75 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aADAM Proteins
650	0	4	_aADAM17 Protein
650	0	4	_aAdministration, Oral
650	0	4	_aAnimals
650	0	4	_aBiological Assay
650	0	4	_aCartilage _xdrug effects
650	0	4	_aCattle
650	0	4	_aDialysis
650	0	4	_aHydroxamic Acids _xchemical synthesis
650	0	4	_aMatrix Metalloproteinase 13
650	0	4	_aMatrix Metalloproteinase Inhibitors
650	0	4	_aMetalloendopeptidases _xantagonists & inhibitors
650	0	4	_aMice
650	0	4	_aOsteoarthritis _xdrug therapy
650	0	4	_aProtease Inhibitors _xchemical synthesis
650	0	4	_aRats
650	0	4	_aStructure-Activity Relationship
650	0	4	_aSulfones _xchemical synthesis
700	1		_aGrosu, George T
700	1		_aDavis, Jamie M
700	1		_aHu, Baihua
700	1		_aEllingboe, John
700	1		_aBaker, Jannie L
700	1		_aSkotnicki, Jerauld S
700	1		_aZask, Arie
700	1		_aDiJoseph, John F
700	1		_aSung, Amy
700	1		_aSharr, Michele A
700	1		_aKillar, Loran M
700	1		_aWalter, Thomas
700	1		_aJin, Guixian
700	1		_aCowling, Rebecca
773	0		_tJournal of medicinal chemistry _gvol. 46 _gno. 12 _gp. 2361-75
856	4	0	_uhttps://doi.org/10.1021/jm0205548 _zAvailable from publisher's website
999			_c12559267 _d12559267