| 000 | 01610 a2200469 4500 | ||
|---|---|---|---|
| 005 | 20250514063137.0 | ||
| 264 | 0 | _c20030912 | |
| 008 | 200309s 0 0 eng d | ||
| 022 | _a0006-4971 | ||
| 024 | 7 |
_a10.1182/blood-2002-11-3622 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aHamilton, David | |
| 245 | 0 | 0 |
_aA novel missense mutation in the gamma-glutamylcysteine synthetase catalytic subunit gene causes both decreased enzymatic activity and glutathione production. _h[electronic resource] |
| 260 |
_bBlood _cJul 2003 |
||
| 300 |
_a725-30 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAmino Acid Substitution |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 | _aBinding Sites |
| 650 | 0 | 4 |
_aCatalytic Domain _xgenetics |
| 650 | 0 | 4 |
_aCells, Cultured _xenzymology |
| 650 | 0 | 4 |
_aCodon _xgenetics |
| 650 | 0 | 4 |
_aFibroblasts _xenzymology |
| 650 | 0 | 4 |
_aGlutamate-Cysteine Ligase _xchemistry |
| 650 | 0 | 4 |
_aGlutathione _xbiosynthesis |
| 650 | 0 | 4 | _aHomozygote |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aKinetics |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 | _aMice, Knockout |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 | _aMutation, Missense |
| 650 | 0 | 4 | _aProtein Conformation |
| 650 | 0 | 4 |
_aRecombinant Fusion Proteins _xmetabolism |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 650 | 0 | 4 | _aTransfection |
| 700 | 1 | _aWu, Jian Hui | |
| 700 | 1 | _aAlaoui-Jamali, Moulay | |
| 700 | 1 | _aBatist, Gerald | |
| 773 | 0 |
_tBlood _gvol. 102 _gno. 2 _gp. 725-30 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1182/blood-2002-11-3622 _zAvailable from publisher's website |
| 999 |
_c12456837 _d12456837 |
||