000			02105 a2200613 4500
005			20250514061324.0
264		0	_c20030403
008			200304s 0 0 eng d
022			_a0950-9232
024	7		_a10.1038/sj.onc.1206101 _2doi
040			_aNLM _beng _cNLM
100	1		_aGreenblatt, M S
245	0	0	_aDetailed computational study of p53 and p16: using evolutionary sequence analysis and disease-associated mutations to predict the functional consequences of allelic variants. _h[electronic resource]
260			_bOncogene _cFeb 2003
300			_a1150-63 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650	0	4	_aAmino Acid Sequence
650	0	4	_aAmino Acid Substitution
650	0	4	_aAnimals
650	0	4	_aBone Neoplasms _xpathology
650	0	4	_aCell Cycle
650	0	4	_aCodon _xgenetics
650	0	4	_aComputational Biology
650	0	4	_aCyclin-Dependent Kinase Inhibitor p16 _xchemistry
650	0	4	_aDatabases, Protein
650	0	4	_aEvolution, Molecular
650	0	4	_aGenes, p16
650	0	4	_aGenes, p53
650	0	4	_aGerm-Line Mutation
650	0	4	_aHumans
650	0	4	_aModels, Molecular
650	0	4	_aMolecular Sequence Data
650	0	4	_aMutagenesis, Site-Directed
650	0	4	_aMutation, Missense
650	0	4	_aOsteosarcoma _xpathology
650	0	4	_aProtein Conformation
650	0	4	_aROC Curve
650	0	4	_aSensitivity and Specificity
650	0	4	_aSequence Alignment
650	0	4	_aSequence Homology, Amino Acid
650	0	4	_aSpecies Specificity
650	0	4	_aTumor Cells, Cultured
650	0	4	_aTumor Suppressor Protein p14ARF _xchemistry
650	0	4	_aTumor Suppressor Protein p53 _xchemistry
650	0	4	_aVertebrates _xgenetics
700	1		_aBeaudet, J G
700	1		_aGump, J R
700	1		_aGodin, K S
700	1		_aTrombley, L
700	1		_aKoh, J
700	1		_aBond, J P
773	0		_tOncogene _gvol. 22 _gno. 8 _gp. 1150-63
856	4	0	_uhttps://doi.org/10.1038/sj.onc.1206101 _zAvailable from publisher's website
999			_c12403125 _d12403125