000 01682 a2200445 4500
005 20250514055527.0
264 0 _c20030728
008 200307s 0 0 eng d
022 _a1433-7851
024 7 _a10.1002/anie.200390115
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aFeling, Robert H
245 0 0 _aSalinosporamide A: a highly cytotoxic proteasome inhibitor from a novel microbial source, a marine bacterium of the new genus salinospora.
_h[electronic resource]
260 _bAngewandte Chemie (International ed. in English)
_cJan 2003
300 _a355-7 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aActinomycetales
_xchemistry
650 0 4 _aAdenocarcinoma
_xmetabolism
650 0 4 _aColonic Neoplasms
_xmetabolism
650 0 4 _aCrystallography, X-Ray
650 0 4 _aCysteine Endopeptidases
650 0 4 _aHumans
650 0 4 _aInhibitory Concentration 50
650 0 4 _aLactones
_xchemistry
650 0 4 _aMagnetic Resonance Spectroscopy
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Structure
650 0 4 _aMultienzyme Complexes
_xantagonists & inhibitors
650 0 4 _aProtease Inhibitors
_xchemistry
650 0 4 _aProteasome Endopeptidase Complex
650 0 4 _aPyrroles
650 0 4 _aTumor Cells, Cultured
700 1 _aBuchanan, Greg O
700 1 _aMincer, Tracy J
700 1 _aKauffman, Christopher A
700 1 _aJensen, Paul R
700 1 _aFenical, William
773 0 _tAngewandte Chemie (International ed. in English)
_gvol. 42
_gno. 3
_gp. 355-7
856 4 0 _uhttps://doi.org/10.1002/anie.200390115
_zAvailable from publisher's website
999 _c12349670
_d12349670