000 02098 a2200565 4500
005 20250514053340.0
264 0 _c20030515
008 200305s 0 0 eng d
022 _a1535-7163
040 _aNLM
_beng
_cNLM
100 1 _aHowells, Lynne M
245 0 0 _aIndole-3-carbinol inhibits protein kinase B/Akt and induces apoptosis in the human breast tumor cell line MDA MB468 but not in the nontumorigenic HBL100 line.
_h[electronic resource]
260 _bMolecular cancer therapeutics
_cNov 2002
300 _a1161-72 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnticarcinogenic Agents
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBreast
_xcytology
650 0 4 _aBreast Neoplasms
_xenzymology
650 0 4 _aCell Division
_xdrug effects
650 0 4 _aDNA, Neoplasm
_xmetabolism
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aI-kappa B Kinase
650 0 4 _aIndoles
_xpharmacology
650 0 4 _aMale
650 0 4 _aNF-kappa B
_xgenetics
650 0 4 _aNecrosis
650 0 4 _aPTEN Phosphohydrolase
650 0 4 _aPhosphatidylinositol 3-Kinases
_xmetabolism
650 0 4 _aPhosphatidylserines
_xmetabolism
650 0 4 _aPhosphoric Monoester Hydrolases
_xmetabolism
650 0 4 _aPhosphorylation
650 0 4 _aPoly(ADP-ribose) Polymerases
_xmetabolism
650 0 4 _aProstatic Neoplasms
_xmetabolism
650 0 4 _aProtein Serine-Threonine Kinases
_xmetabolism
650 0 4 _aProto-Oncogene Proteins
_xantagonists & inhibitors
650 0 4 _aProto-Oncogene Proteins c-akt
650 0 4 _aProto-Oncogene Proteins c-bcl-2
_xmetabolism
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aTumor Cells, Cultured
650 0 4 _aTumor Suppressor Proteins
_xmetabolism
650 0 4 _abcl-2-Associated X Protein
650 0 4 _abcl-X Protein
700 1 _aGallacher-Horley, Barbara
700 1 _aHoughton, Catherine E
700 1 _aManson, Margaret M
700 1 _aHudson, E Ann
773 0 _tMolecular cancer therapeutics
_gvol. 1
_gno. 13
_gp. 1161-72
999 _c12284389
_d12284389