000			02219 a2200577 4500
005			20250514052437.0
264		0	_c20021223
008			200212s 0 0 eng d
022			_a1529-2401
040			_aNLM _beng _cNLM
100	1		_aAzzouz, Mimoun
245	0	0	_aMulticistronic lentiviral vector-mediated striatal gene transfer of aromatic L-amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained transgene expression, dopamine production, and functional improvement in a rat model of Parkinson's disease. _h[electronic resource]
260			_bThe Journal of neuroscience : the official journal of the Society for Neuroscience _cDec 2002
300			_a10302-12 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAnimals
650	0	4	_aAromatic-L-Amino-Acid Decarboxylases _xadministration & dosage
650	0	4	_aCatecholamines _xmetabolism
650	0	4	_aCells, Cultured
650	0	4	_aCorpus Striatum _xdrug effects
650	0	4	_aDisease Models, Animal
650	0	4	_aDopamine _xbiosynthesis
650	0	4	_aGTP Cyclohydrolase _xadministration & dosage
650	0	4	_aGene Expression _xdrug effects
650	0	4	_aGene Transfer Techniques
650	0	4	_aGenes _xgenetics
650	0	4	_aGenetic Therapy _xmethods
650	0	4	_aGenetic Vectors _xadministration & dosage
650	0	4	_aHumans
650	0	4	_aKidney _xcytology
650	0	4	_aLentivirus _xgenetics
650	0	4	_aMale
650	0	4	_aNeurons _xcytology
650	0	4	_aOxidopamine
650	0	4	_aParkinsonian Disorders _xchemically induced
650	0	4	_aRats
650	0	4	_aRats, Wistar
650	0	4	_aRecovery of Function _xdrug effects
650	0	4	_aTransgenes
650	0	4	_aTreatment Outcome
650	0	4	_aTyrosine 3-Monooxygenase _xadministration & dosage
700	1		_aMartin-Rendon, Enca
700	1		_aBarber, Robert D
700	1		_aMitrophanous, Kyriacos A
700	1		_aCarter, Emma E
700	1		_aRohll, Jonathan B
700	1		_aKingsman, Susan M
700	1		_aKingsman, Alan J
700	1		_aMazarakis, Nicholas D
773	0		_tThe Journal of neuroscience : the official journal of the Society for Neuroscience _gvol. 22 _gno. 23 _gp. 10302-12
999			_c12257368 _d12257368