000 | 01715 a2200469 4500 | ||
---|---|---|---|
005 | 20250514051751.0 | ||
264 | 0 | _c20021220 | |
008 | 200212s 0 0 eng d | ||
022 | _a0022-2623 | ||
024 | 7 |
_a10.1021/jm0209331 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aMacKenzie, A Roderick | |
245 | 0 | 0 |
_aStructure-activity relationships of 1-alkyl-5-(3,4-dichlorophenyl)- 5-[2-[(3-substituted)-1-azetidinyl]ethyl]-2-piperidones. 1. Selective antagonists of the neurokinin-2 receptor. _h[electronic resource] |
260 |
_bJournal of medicinal chemistry _cNov 2002 |
||
300 |
_a5365-77 p. _bdigital |
||
500 | _aPublication Type: Journal Article | ||
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aAzetidines _xchemical synthesis |
650 | 0 | 4 | _aCHO Cells |
650 | 0 | 4 | _aCricetinae |
650 | 0 | 4 | _aDrug Stability |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aIn Vitro Techniques |
650 | 0 | 4 |
_aMicrosomes, Liver _xmetabolism |
650 | 0 | 4 |
_aMuscle Contraction _xdrug effects |
650 | 0 | 4 |
_aMuscle, Smooth _xdrug effects |
650 | 0 | 4 |
_aPiperazines _xchemical synthesis |
650 | 0 | 4 |
_aPiperidones _xchemical synthesis |
650 | 0 | 4 |
_aPulmonary Artery _xdrug effects |
650 | 0 | 4 | _aRabbits |
650 | 0 | 4 | _aRadioligand Assay |
650 | 0 | 4 |
_aReceptors, Neurokinin-2 _xantagonists & inhibitors |
650 | 0 | 4 |
_aReceptors, Neurokinin-3 _xmetabolism |
650 | 0 | 4 | _aStereoisomerism |
650 | 0 | 4 | _aStructure-Activity Relationship |
700 | 1 | _aMarchington, Allan P | |
700 | 1 | _aMiddleton, Donald S | |
700 | 1 | _aNewman, Sandra D | |
700 | 1 | _aJones, Barry C | |
773 | 0 |
_tJournal of medicinal chemistry _gvol. 45 _gno. 24 _gp. 5365-77 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm0209331 _zAvailable from publisher's website |
999 |
_c12238154 _d12238154 |