000 01924 a2200541 4500
005 20250514051420.0
264 0 _c20030520
008 200305s 0 0 eng d
022 _a0960-894X
024 7 _a10.1016/s0960-894x(02)00789-8
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSlater, Martin J
245 0 0 _aDesign and synthesis of ethyl pyrrolidine-5,5-trans-lactams as inhibitors of hepatitis C virus NS3/4A protease.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_cDec 2002
300 _a3359-62 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAmino Acid Sequence
650 0 4 _aCarrier Proteins
_xantagonists & inhibitors
650 0 4 _aDrug Design
650 0 4 _aHepacivirus
_xdrug effects
650 0 4 _aHumans
650 0 4 _aInhibitory Concentration 50
650 0 4 _aIntracellular Signaling Peptides and Proteins
650 0 4 _aLactams
_xchemical synthesis
650 0 4 _aMicrobial Sensitivity Tests
650 0 4 _aPyrrolidines
_xchemical synthesis
650 0 4 _aSerine Proteinase Inhibitors
_xchemical synthesis
650 0 4 _aStereoisomerism
650 0 4 _aStructure-Activity Relationship
650 0 4 _aViral Nonstructural Proteins
_xantagonists & inhibitors
650 0 4 _aViral Proteins
_xantagonists & inhibitors
700 1 _aAndrews, David M
700 1 _aBaker, Graham
700 1 _aBethell, Susanne S
700 1 _aCarey, Seb
700 1 _aChaignot, Helene
700 1 _aClarke, Berwyn
700 1 _aCoomber, Barry
700 1 _aEllis, Malcolm
700 1 _aGood, Andrew
700 1 _aGray, Norman
700 1 _aHardy, George
700 1 _aJones, Paul
700 1 _aMills, Gail
700 1 _aRobinson, Ed
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 12
_gno. 23
_gp. 3359-62
856 4 0 _uhttps://doi.org/10.1016/s0960-894x(02)00789-8
_zAvailable from publisher's website
999 _c12227024
_d12227024