000 02253 a2200613 4500
005 20250514050627.0
264 0 _c20021209
008 200212s 0 0 eng d
022 _a0270-9139
024 7 _a10.1053/jhep.2002.36160
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aCoutant, Alexandre
245 0 0 _aPI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival.
_h[electronic resource]
260 _bHepatology (Baltimore, Md.)
_cNov 2002
300 _a1079-88 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aCarrier Proteins
_xmetabolism
650 0 4 _aCell Division
_xphysiology
650 0 4 _aCell Survival
_xphysiology
650 0 4 _aCells, Cultured
650 0 4 _aCyclin D1
_xmetabolism
650 0 4 _aDNA
_xbiosynthesis
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aEpidermal Growth Factor
_xpharmacology
650 0 4 _aG1 Phase
_xphysiology
650 0 4 _aHepatocytes
_xcytology
650 0 4 _aInsulin
_xmetabolism
650 0 4 _aIntracellular Signaling Peptides and Proteins
650 0 4 _aMAP Kinase Kinase Kinase 1
650 0 4 _aMAP Kinase Signaling System
_xdrug effects
650 0 4 _aMale
650 0 4 _aMitogen-Activated Protein Kinases
_xmetabolism
650 0 4 _aPhosphatidylinositol 3-Kinases
_xmetabolism
650 0 4 _aPhosphoinositide-3 Kinase Inhibitors
650 0 4 _aPhosphoproteins
_xmetabolism
650 0 4 _aPhosphorylation
650 0 4 _aProtein Biosynthesis
650 0 4 _aProtein Kinases
_xmetabolism
650 0 4 _aProtein Serine-Threonine Kinases
_xmetabolism
650 0 4 _aProto-Oncogene Proteins
_xmetabolism
650 0 4 _aProto-Oncogene Proteins c-akt
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aS Phase
_xphysiology
650 0 4 _aTOR Serine-Threonine Kinases
700 1 _aRescan, Claude
700 1 _aGilot, David
700 1 _aLoyer, Pascal
700 1 _aGuguen-Guillouzo, Christiane
700 1 _aBaffet, Georges
773 0 _tHepatology (Baltimore, Md.)
_gvol. 36
_gno. 5
_gp. 1079-88
856 4 0 _uhttps://doi.org/10.1053/jhep.2002.36160
_zAvailable from publisher's website
999 _c12204097
_d12204097