000 01531 a2200409 4500
005 20250514050244.0
264 0 _c20021113
008 200211s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm020198t
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aDesiraju, G R
245 0 0 _aComputer-aided design of selective COX-2 inhibitors: comparative molecular field analysis, comparative molecular similarity indices analysis, and docking studies of some 1,2-diarylimidazole derivatives.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cOct 2002
300 _a4847-57 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article
650 0 4 _aBinding Sites
650 0 4 _aCyclooxygenase 1
650 0 4 _aCyclooxygenase 2
650 0 4 _aCyclooxygenase 2 Inhibitors
650 0 4 _aCyclooxygenase Inhibitors
_xchemistry
650 0 4 _aDrug Design
650 0 4 _aImidazoles
_xchemistry
650 0 4 _aIsoenzymes
_xchemistry
650 0 4 _aMolecular Conformation
650 0 4 _aProstaglandin-Endoperoxide Synthases
_xchemistry
650 0 4 _aQuantitative Structure-Activity Relationship
700 1 _aGopalakrishnan, B
700 1 _aJetti, R K R
700 1 _aNagaraju, A
700 1 _aRaveendra, D
700 1 _aSarma, J A R P
700 1 _aSobhia, M E
700 1 _aThilagavathi, R
773 0 _tJournal of medicinal chemistry
_gvol. 45
_gno. 22
_gp. 4847-57
856 4 0 _uhttps://doi.org/10.1021/jm020198t
_zAvailable from publisher's website
999 _c12192382
_d12192382