000 02107 a2200565 4500
005 20250514042702.0
264 0 _c20020924
008 200209s 0 0 eng d
022 _a0092-8674
024 7 _a10.1016/s0092-8674(02)00872-3
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aYang, Tong
245 0 0 _aCrucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER.
_h[electronic resource]
260 _bCell
_cAug 2002
300 _a489-500 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aCCAAT-Enhancer-Binding Proteins
_xmetabolism
650 0 4 _aCell Membrane
_xmetabolism
650 0 4 _aCells, Cultured
650 0 4 _aCholesterol
_xbiosynthesis
650 0 4 _aDNA-Binding Proteins
_xmetabolism
650 0 4 _aEndoplasmic Reticulum
_xmetabolism
650 0 4 _aEukaryotic Cells
_xcytology
650 0 4 _aGene Expression Regulation
_xphysiology
650 0 4 _aGenetic Vectors
_xphysiology
650 0 4 _aGolgi Apparatus
_xmetabolism
650 0 4 _aHomeostasis
_xgenetics
650 0 4 _aHumans
650 0 4 _aIntracellular Signaling Peptides and Proteins
650 0 4 _aMembrane Proteins
_xgenetics
650 0 4 _aMutation
_xgenetics
650 0 4 _aPeptide Hydrolases
_xmetabolism
650 0 4 _aProtein Binding
_xphysiology
650 0 4 _aProtein Structure, Tertiary
_xphysiology
650 0 4 _aProtein Transport
_xphysiology
650 0 4 _aProteins
_xgenetics
650 0 4 _aSterol Regulatory Element Binding Protein 1
650 0 4 _aSterols
_xmetabolism
650 0 4 _aTranscription Factors
650 0 4 _aTransfection
700 1 _aEspenshade, Peter J
700 1 _aWright, Michael E
700 1 _aYabe, Daisuke
700 1 _aGong, Yi
700 1 _aAebersold, Ruedi
700 1 _aGoldstein, Joseph L
700 1 _aBrown, Michael S
773 0 _tCell
_gvol. 110
_gno. 4
_gp. 489-500
856 4 0 _uhttps://doi.org/10.1016/s0092-8674(02)00872-3
_zAvailable from publisher's website
999 _c12083357
_d12083357