000			02102 a2200637 4500
005			20250514042330.0
264		0	_c20020923
008			200209s 0 0 eng d
022			_a0022-2623
024	7		_a10.1021/jm020138n _2doi
040			_aNLM _beng _cNLM
100	1		_aMurugesan, Natesan
245	0	0	_aDiscovery of N-isoxazolyl biphenylsulfonamides as potent dual angiotensin II and endothelin A receptor antagonists. _h[electronic resource]
260			_bJournal of medicinal chemistry _cAug 2002
300			_a3829-35 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAngiotensin II _xmetabolism
650	0	4	_aAngiotensin Receptor Antagonists
650	0	4	_aAnimals
650	0	4	_aAntihypertensive Agents _xchemical synthesis
650	0	4	_aBlood Pressure _xdrug effects
650	0	4	_aCHO Cells
650	0	4	_aCricetinae
650	0	4	_aCrystallography, X-Ray
650	0	4	_aEndothelin Receptor Antagonists
650	0	4	_aIsoxazoles _xchemical synthesis
650	0	4	_aMolecular Structure
650	0	4	_aRadioligand Assay
650	0	4	_aRats
650	0	4	_aReceptor, Angiotensin, Type 1
650	0	4	_aReceptor, Endothelin A
650	0	4	_aStructure-Activity Relationship
650	0	4	_aSulfonamides _xchemical synthesis
700	1		_aTellew, John E
700	1		_aGu, Zhengxiang
700	1		_aKunst, Bridgette L
700	1		_aFadnis, Leena
700	1		_aCornelius, Lyndon A
700	1		_aBaska, Rose Ann F
700	1		_aYang, Yifan
700	1		_aBeyer, Sophie M
700	1		_aMonshizadegan, Hossain
700	1		_aDickinson, Kenneth E
700	1		_aPanchal, Balkrushna
700	1		_aValentine, Maria T
700	1		_aChong, Saeho
700	1		_aMorrison, Richard A
700	1		_aCarlson, Kenneth E
700	1		_aPowell, James R
700	1		_aMoreland, Suzanne
700	1		_aBarrish, Joel C
700	1		_aKowala, Mark C
700	1		_aMacor, John E
773	0		_tJournal of medicinal chemistry _gvol. 45 _gno. 18 _gp. 3829-35
856	4	0	_uhttps://doi.org/10.1021/jm020138n _zAvailable from publisher's website
999			_c12072481 _d12072481