000			02013 a2200481 4500
005			20250514042128.0
264		0	_c20020918
008			200209s 0 0 eng d
022			_a0022-3565
024	7		_a10.1124/jpet.302.3.1184 _2doi
040			_aNLM _beng _cNLM
100	1		_aZhang, Fengqin
245	0	0	_a(-)U50,488H [(trans)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]benzeneacetamide] induces internalization and down-regulation of the human, but not the rat, kappa-opioid receptor: structural basis for the differential regulation. _h[electronic resource]
260			_bThe Journal of pharmacology and experimental therapeutics _cSep 2002
300			_a1184-92 p. _bdigital
500			_aPublication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
650	0	4	_a3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer _xpharmacology
650	0	4	_aAmino Acid Sequence
650	0	4	_aAnalgesics, Non-Narcotic _xpharmacology
650	0	4	_aAnimals
650	0	4	_aCHO Cells
650	0	4	_aCell Membrane _xmetabolism
650	0	4	_aCricetinae
650	0	4	_aDiprenorphine _xmetabolism
650	0	4	_aDown-Regulation _xdrug effects
650	0	4	_aFluorescent Antibody Technique, Direct
650	0	4	_aHumans
650	0	4	_aIntracellular Membranes _xmetabolism
650	0	4	_aIonophores _xpharmacology
650	0	4	_aMolecular Sequence Data
650	0	4	_aMonensin _xpharmacology
650	0	4	_aMutation _xdrug effects
650	0	4	_aNarcotic Antagonists _xmetabolism
650	0	4	_aRats
650	0	4	_aReceptors, Opioid, kappa _xbiosynthesis
650	0	4	_aRecombinant Fusion Proteins _xchemistry
650	0	4	_aSpecies Specificity
700	1		_aLi, Jin
700	1		_aLi, Jian-Guo
700	1		_aLiu-Chen, Lee-Yuan
773	0		_tThe Journal of pharmacology and experimental therapeutics _gvol. 302 _gno. 3 _gp. 1184-92
856	4	0	_uhttps://doi.org/10.1124/jpet.302.3.1184 _zAvailable from publisher's website
999			_c12066075 _d12066075