000			02092 a2200565 4500
005			20250514031326.0
264		0	_c20020513
008			200205s 0 0 eng d
022			_a0022-3565
024	7		_a10.1124/jpet.301.2.561 _2doi
040			_aNLM _beng _cNLM
100	1		_aKang, Young Jin
245	0	0	_aA synthetic isoquinoline alkaloid, 1-(beta-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (YS 51), reduces inducible nitric oxide synthase expression and improves survival in a rodent model of endotoxic shock. _h[electronic resource]
260			_bThe Journal of pharmacology and experimental therapeutics _cMay 2002
300			_a561-7 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAnimals
650	0	4	_aAorta _xdrug effects
650	0	4	_aCell Line
650	0	4	_aDNA _xdrug effects
650	0	4	_aDisease Models, Animal
650	0	4	_aDrug Interactions
650	0	4	_aFibrinolytic Agents _xchemical synthesis
650	0	4	_aGene Expression _xdrug effects
650	0	4	_aIsoquinolines _xchemical synthesis
650	0	4	_aLipopolysaccharides _xpharmacology
650	0	4	_aMale
650	0	4	_aMice
650	0	4	_aMice, Inbred ICR
650	0	4	_aNF-kappa B _xmetabolism
650	0	4	_aNitrates _xblood
650	0	4	_aNitric Oxide _xmetabolism
650	0	4	_aNitric Oxide Synthase _xgenetics
650	0	4	_aNitric Oxide Synthase Type II
650	0	4	_aNitrites _xblood
650	0	4	_aPromoter Regions, Genetic _xdrug effects
650	0	4	_aRNA, Messenger _xdrug effects
650	0	4	_aRats
650	0	4	_aRats, Sprague-Dawley
650	0	4	_aShock, Septic _xblood
650	0	4	_aSurvival Rate
650	0	4	_aTetrahydroisoquinolines
700	1		_aSeo, Sook Jae
700	1		_aYun-Choi, Hye Sook
700	1		_aLee, Duk Hyung
700	1		_aKim, Young-Myung
700	1		_aChang, Ki Churl
773	0		_tThe Journal of pharmacology and experimental therapeutics _gvol. 301 _gno. 2 _gp. 561-7
856	4	0	_uhttps://doi.org/10.1124/jpet.301.2.561 _zAvailable from publisher's website
999			_c11863450 _d11863450