000 01631 a2200481 4500
005 20250514031118.0
264 0 _c20020430
008 200204s 0 0 eng d
022 _a0007-0920
024 7 _a10.1038/sj.bjc.6600208
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMaring, J G
245 0 0 _aReduced 5-FU clearance in a patient with low DPD activity due to heterozygosity for a mutant allele of the DPYD gene.
_h[electronic resource]
260 _bBritish journal of cancer
_cApr 2002
300 _a1028-33 p.
_bdigital
500 _aPublication Type: Case Reports; Journal Article
650 0 4 _aAged
650 0 4 _aAlleles
650 0 4 _aAntimetabolites, Antineoplastic
_xadverse effects
650 0 4 _aChromatography, High Pressure Liquid
650 0 4 _aColorectal Neoplasms
_xdrug therapy
650 0 4 _aDNA, Neoplasm
_xgenetics
650 0 4 _aDihydrouracil Dehydrogenase (NADP)
650 0 4 _aFemale
650 0 4 _aFluorouracil
_xadverse effects
650 0 4 _aHumans
650 0 4 _aLeucovorin
_xadministration & dosage
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aOxidoreductases
_xgenetics
650 0 4 _aPoint Mutation
650 0 4 _aPolymerase Chain Reaction
650 0 4 _aSequence Analysis, DNA
700 1 _avan Kuilenburg, A B P
700 1 _aHaasjes, J
700 1 _aPiersma, H
700 1 _aGroen, H J M
700 1 _aUges, D R A
700 1 _aVan Gennip, A H
700 1 _aDe Vries, E G E
773 0 _tBritish journal of cancer
_gvol. 86
_gno. 7
_gp. 1028-33
856 4 0 _uhttps://doi.org/10.1038/sj.bjc.6600208
_zAvailable from publisher's website
999 _c11856610
_d11856610