000 01895 a2200457 4500
005 20250514021822.0
264 0 _c20020212
008 200202s 0 0 eng d
022 _a0008-5472
040 _aNLM
_beng
_cNLM
100 1 _aJeffy, Brandon D
245 0 0 _aActivation of the aromatic hydrocarbon receptor pathway is not sufficient for transcriptional repression of BRCA-1: requirements for metabolism of benzo[a]pyrene to 7r,8t-dihydroxy-9t,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.
_h[electronic resource]
260 _bCancer research
_cJan 2002
300 _a113-21 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
650 0 4 _a7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
_xmetabolism
650 0 4 _aBRCA1 Protein
_xbiosynthesis
650 0 4 _aBenzo(a)pyrene
_xmetabolism
650 0 4 _aBiotransformation
650 0 4 _aBreast Neoplasms
_xchemically induced
650 0 4 _aCarcinogens
_xmetabolism
650 0 4 _aDown-Regulation
650 0 4 _aGene Expression Profiling
650 0 4 _aGene Expression Regulation, Neoplastic
_xdrug effects
650 0 4 _aGenes, BRCA1
_xdrug effects
650 0 4 _aHumans
650 0 4 _aPolychlorinated Dibenzodioxins
_xtoxicity
650 0 4 _aPromoter Regions, Genetic
_xdrug effects
650 0 4 _aRNA, Messenger
_xbiosynthesis
650 0 4 _aReceptors, Aryl Hydrocarbon
_xmetabolism
650 0 4 _aReverse Transcriptase Polymerase Chain Reaction
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aTranscription, Genetic
_xdrug effects
650 0 4 _aTumor Cells, Cultured
650 0 4 _aTumor Suppressor Protein p53
_xgenetics
700 1 _aChirnomas, Ryan B
700 1 _aChen, Eddy J
700 1 _aGudas, Jean M
700 1 _aRomagnolo, Donato F
773 0 _tCancer research
_gvol. 62
_gno. 1
_gp. 113-21
999 _c11693978
_d11693978