000 01563 a2200421 4500
005 20250514020927.0
264 0 _c20020122
008 200201s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm010924c
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBaraldi, Pier Giovanni
245 0 0 _a7-Substituted 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonists: a study on the importance of modifications at the side chain on the activity and solubility.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cJan 2002
300 _a115-26 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aBinding, Competitive
650 0 4 _aChromatography, Thin Layer
650 0 4 _aDrug Design
650 0 4 _aFurans
_xchemical synthesis
650 0 4 _aHumans
650 0 4 _aPurinergic P1 Receptor Antagonists
650 0 4 _aPyrimidines
_xchemical synthesis
650 0 4 _aRadioligand Assay
650 0 4 _aReceptor, Adenosine A2A
650 0 4 _aReceptors, Purinergic P1
_xmetabolism
650 0 4 _aSolubility
650 0 4 _aStructure-Activity Relationship
700 1 _aCacciari, Barbara
700 1 _aRomagnoli, Romeo
700 1 _aSpalluto, Giampiero
700 1 _aMonopoli, Angela
700 1 _aOngini, Ennio
700 1 _aVarani, Katia
700 1 _aBorea, Pier Andrea
773 0 _tJournal of medicinal chemistry
_gvol. 45
_gno. 1
_gp. 115-26
856 4 0 _uhttps://doi.org/10.1021/jm010924c
_zAvailable from publisher's website
999 _c11666999
_d11666999