000 01540 a2200433 4500
005 20250514010137.0
264 0 _c20011011
008 200110s 0 0 eng d
022 _a0022-538X
024 7 _a10.1128/JVI.75.19.9378-9392.2001
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHanna, Z
245 0 0 _aThe pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck.
_h[electronic resource]
260 _bJournal of virology
_cOct 2001
300 _a9378-92 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aCD4 Antigens
_xgenetics
650 0 4 _aGenes, nef
650 0 4 _aHIV Infections
_xgenetics
650 0 4 _aHIV-1
_xgenetics
650 0 4 _aHumans
650 0 4 _aMice
650 0 4 _aMice, Transgenic
650 0 4 _aMutation
650 0 4 _aProtein-Tyrosine Kinases
_xgenetics
650 0 4 _aProto-Oncogene Proteins
_xgenetics
650 0 4 _aProto-Oncogene Proteins c-hck
650 0 4 _aVirulence
_xgenetics
650 0 4 _aVirus Replication
_xgenetics
650 0 4 _asrc Homology Domains
700 1 _aWeng, X
700 1 _aKay, D G
700 1 _aPoudrier, J
700 1 _aLowell, C
700 1 _aJolicoeur, P
773 0 _tJournal of virology
_gvol. 75
_gno. 19
_gp. 9378-92
856 4 0 _uhttps://doi.org/10.1128/JVI.75.19.9378-9392.2001
_zAvailable from publisher's website
999 _c11457025
_d11457025