000 02031 a2200589 4500
005 20250514005927.0
264 0 _c20011205
008 200112s 0 0 eng d
022 _a0223-5234
024 7 _a10.1016/s0223-5234(01)01251-x
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aCaliendo, G
245 0 0 _aSynthesis of substituted benzamides as anti-inflammatory agents that inhibit preferentially cyclooxygenase 1 but do not cause gastric damage.
_h[electronic resource]
260 _bEuropean journal of medicinal chemistry
_cJun 2001
300 _a517-30 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAnti-Inflammatory Agents
_xadverse effects
650 0 4 _aBenzamides
_xadverse effects
650 0 4 _aCyclooxygenase 1
650 0 4 _aCyclooxygenase 2
650 0 4 _aCyclooxygenase 2 Inhibitors
650 0 4 _aCyclooxygenase Inhibitors
_xadverse effects
650 0 4 _aDrug Design
650 0 4 _aDrug Evaluation, Preclinical
650 0 4 _aEdema
_xchemically induced
650 0 4 _aFood Deprivation
650 0 4 _aInhibitory Concentration 50
650 0 4 _aIsoenzymes
_xantagonists & inhibitors
650 0 4 _aMagnetic Resonance Spectroscopy
650 0 4 _aMale
650 0 4 _aMembrane Proteins
650 0 4 _aProstaglandin-Endoperoxide Synthases
_xmetabolism
650 0 4 _aRats
650 0 4 _aRats, Wistar
650 0 4 _aSheep
650 0 4 _aStomach
_xdrug effects
650 0 4 _aStructure-Activity Relationship
650 0 4 _aSubstrate Specificity
700 1 _aSantagada, V
700 1 _aPerissutti, E
700 1 _aSeverino, B
700 1 _aFiorino, F
700 1 _aWarner, T D
700 1 _aWallace, J L
700 1 _aIfa, D R
700 1 _aAntunes, E
700 1 _aCirino, G
700 1 _ade Nucci, G
773 0 _tEuropean journal of medicinal chemistry
_gvol. 36
_gno. 6
_gp. 517-30
856 4 0 _uhttps://doi.org/10.1016/s0223-5234(01)01251-x
_zAvailable from publisher's website
999 _c11450010
_d11450010