000 02291 a2200625 4500
005 20250514005713.0
264 0 _c20010920
008 200109s 0 0 eng d
022 _a0021-9738
024 7 _a10.1172/JCI12821
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMonteleone, G
245 0 0 _aBlocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease.
_h[electronic resource]
260 _bThe Journal of clinical investigation
_cAug 2001
300 _a601-9 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aActivin Receptors, Type I
650 0 4 _aAdolescent
650 0 4 _aAdult
650 0 4 _aCells, Cultured
_xdrug effects
650 0 4 _aChild
650 0 4 _aColitis, Ulcerative
_xmetabolism
650 0 4 _aCrohn Disease
_xmetabolism
650 0 4 _aCytokines
_xbiosynthesis
650 0 4 _aDNA-Binding Proteins
_xantagonists & inhibitors
650 0 4 _aFemale
650 0 4 _aGene Expression Regulation
_xdrug effects
650 0 4 _aHumans
650 0 4 _aInflammatory Bowel Diseases
_xmetabolism
650 0 4 _aInterferon-gamma
_xbiosynthesis
650 0 4 _aIntestinal Mucosa
_xdrug effects
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aOligodeoxyribonucleotides, Antisense
_xpharmacology
650 0 4 _aOrgan Culture Techniques
650 0 4 _aPhosphorylation
650 0 4 _aProtein Processing, Post-Translational
650 0 4 _aProtein Serine-Threonine Kinases
_xdrug effects
650 0 4 _aReceptor, Transforming Growth Factor-beta Type I
650 0 4 _aReceptors, Transforming Growth Factor beta
_xdrug effects
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aSmad3 Protein
650 0 4 _aSmad7 Protein
650 0 4 _aTrans-Activators
_xantagonists & inhibitors
650 0 4 _aTransforming Growth Factor beta
_xphysiology
650 0 4 _aTransforming Growth Factor beta1
650 0 4 _aTumor Necrosis Factor-alpha
_xbiosynthesis
700 1 _aKumberova, A
700 1 _aCroft, N M
700 1 _aMcKenzie, C
700 1 _aSteer, H W
700 1 _aMacDonald, T T
773 0 _tThe Journal of clinical investigation
_gvol. 108
_gno. 4
_gp. 601-9
856 4 0 _uhttps://doi.org/10.1172/JCI12821
_zAvailable from publisher's website
999 _c11443153
_d11443153