000			02269 a2200625 4500
005			20250514002059.0
264		0	_c20010719
008			200107s 0 0 eng d
022			_a1524-4539
024	7		_a10.1161/01.cir.103.23.e119 _2doi
040			_aNLM _beng _cNLM
100	1		_aButrous, G
245	0	0	_aSildenafil (Viagra) prolongs cardiac repolarization by blocking the rapid component of the delayed rectifier potassium current. _h[electronic resource]
260			_bCirculation _cJun 2001
300			_aE119-20; author reply E119-20 p. _bdigital
500			_aPublication Type: Letter; Comment
650	0	4	_a3',5'-Cyclic-GMP Phosphodiesterases _xantagonists & inhibitors
650	0	4	_aAdministration, Oral
650	0	4	_aAnimals
650	0	4	_aBiological Availability
650	0	4	_aCation Transport Proteins
650	0	4	_aCells, Cultured
650	0	4	_aCricetinae
650	0	4	_aCyclic Nucleotide Phosphodiesterases, Type 5
650	0	4	_aCytochrome P-450 CYP3A
650	0	4	_aCytochrome P-450 Enzyme Inhibitors
650	0	4	_aCytochrome P-450 Enzyme System _xmetabolism
650	0	4	_aDNA-Binding Proteins
650	0	4	_aDogs
650	0	4	_aDose-Response Relationship, Drug
650	0	4	_aERG1 Potassium Channel
650	0	4	_aElectrocardiography _xdrug effects
650	0	4	_aErectile Dysfunction _xdrug therapy
650	0	4	_aErythromycin _xpharmacology
650	0	4	_aEther-A-Go-Go Potassium Channels
650	0	4	_aGuinea Pigs
650	0	4	_aHeart _xdrug effects
650	0	4	_aHeart Conduction System _xdrug effects
650	0	4	_aHumans
650	0	4	_aMale
650	0	4	_aMixed Function Oxygenases _xantagonists & inhibitors
650	0	4	_aMyocardium _xmetabolism
650	0	4	_aPiperazines _xadministration & dosage
650	0	4	_aPotassium Channel Blockers
650	0	4	_aPotassium Channels _xmetabolism
650	0	4	_aPotassium Channels, Voltage-Gated
650	0	4	_aPurines
650	0	4	_aSildenafil Citrate
650	0	4	_aSulfones
650	0	4	_aTrans-Activators
650	0	4	_aTranscriptional Regulator ERG
700	1		_aSiegel, R L
773	0		_tCirculation _gvol. 103 _gno. 23 _gp. E119-20; author reply E119-20
856	4	0	_uhttps://doi.org/10.1161/01.cir.103.23.e119 _zAvailable from publisher's website
999			_c11332406 _d11332406