| 000 | 02498 a2200733 4500 | ||
|---|---|---|---|
| 005 | 20250514001056.0 | ||
| 264 | 0 | _c20010628 | |
| 008 | 200106s 0 0 eng d | ||
| 022 | _a0006-4971 | ||
| 024 | 7 |
_a10.1182/blood.v97.11.3361 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aKarp, J E | |
| 245 | 0 | 0 |
_aClinical and biologic activity of the farnesyltransferase inhibitor R115777 in adults with refractory and relapsed acute leukemias: a phase 1 clinical-laboratory correlative trial. _h[electronic resource] |
| 260 |
_bBlood _cJun 2001 |
||
| 300 |
_a3361-9 p. _bdigital |
||
| 500 | _aPublication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. | ||
| 650 | 0 | 4 | _aAdult |
| 650 | 0 | 4 | _aAged |
| 650 | 0 | 4 |
_aAlkyl and Aryl Transferases _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aBone Marrow _xmetabolism |
| 650 | 0 | 4 | _aCohort Studies |
| 650 | 0 | 4 | _aDose-Response Relationship, Drug |
| 650 | 0 | 4 |
_aEnzyme Activation _xdrug effects |
| 650 | 0 | 4 |
_aEnzyme Inhibitors _xadverse effects |
| 650 | 0 | 4 | _aFarnesyltranstransferase |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 | _aGenes, ras |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aLeukemia, Myelogenous, Chronic, BCR-ABL Positive _xdrug therapy |
| 650 | 0 | 4 |
_aLeukemia, Myeloid, Acute _xdrug therapy |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 | _aMiddle Aged |
| 650 | 0 | 4 |
_aMitogen-Activated Protein Kinase 1 _xmetabolism |
| 650 | 0 | 4 | _aMitogen-Activated Protein Kinase 3 |
| 650 | 0 | 4 |
_aMitogen-Activated Protein Kinases _xmetabolism |
| 650 | 0 | 4 | _aMutation |
| 650 | 0 | 4 | _aPhosphorylation |
| 650 | 0 | 4 |
_aPrecursor Cell Lymphoblastic Leukemia-Lymphoma _xdrug therapy |
| 650 | 0 | 4 | _aProtein Prenylation |
| 650 | 0 | 4 |
_aQuinolones _xadverse effects |
| 650 | 0 | 4 | _aRecurrence |
| 650 | 0 | 4 | _aRemission Induction |
| 650 | 0 | 4 | _aTreatment Outcome |
| 700 | 1 | _aLancet, J E | |
| 700 | 1 | _aKaufmann, S H | |
| 700 | 1 | _aEnd, D W | |
| 700 | 1 | _aWright, J J | |
| 700 | 1 | _aBol, K | |
| 700 | 1 | _aHorak, I | |
| 700 | 1 | _aTidwell, M L | |
| 700 | 1 | _aLiesveld, J | |
| 700 | 1 | _aKottke, T J | |
| 700 | 1 | _aAnge, D | |
| 700 | 1 | _aBuddharaju, L | |
| 700 | 1 | _aGojo, I | |
| 700 | 1 | _aHighsmith, W E | |
| 700 | 1 | _aBelly, R T | |
| 700 | 1 | _aHohl, R J | |
| 700 | 1 | _aRybak, M E | |
| 700 | 1 | _aThibault, A | |
| 700 | 1 | _aRosenblatt, J | |
| 773 | 0 |
_tBlood _gvol. 97 _gno. 11 _gp. 3361-9 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1182/blood.v97.11.3361 _zAvailable from publisher's website |
| 999 |
_c11301543 _d11301543 |
||