000 01920 a2200529 4500
005 20250514000716.0
264 0 _c20010614
008 200106s 0 0 eng d
022 _a0022-3565
040 _aNLM
_beng
_cNLM
100 1 _aPonnappa, B C
245 0 0 _aIn vivo delivery of antisense oligonucleotides in pH-sensitive liposomes inhibits lipopolysaccharide-induced production of tumor necrosis factor-alpha in rats.
_h[electronic resource]
260 _bThe Journal of pharmacology and experimental therapeutics
_cJun 2001
300 _a1129-36 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAnimals
650 0 4 _aChemical and Drug Induced Liver Injury
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Delivery Systems
_xmethods
650 0 4 _aDrug Stability
650 0 4 _aEndosomes
650 0 4 _aHydrogen-Ion Concentration
650 0 4 _aIn Vitro Techniques
650 0 4 _aInjections, Intravenous
650 0 4 _aLipopolysaccharides
_xpharmacology
650 0 4 _aLiposomes
650 0 4 _aLiver
_xdrug effects
650 0 4 _aLiver Diseases
_xmetabolism
650 0 4 _aMale
650 0 4 _aOligonucleotides, Antisense
_xadministration & dosage
650 0 4 _aOrganothiophosphorus Compounds
_xadministration & dosage
650 0 4 _aPhosphorothioate Oligonucleotides
650 0 4 _aRNA, Messenger
_xantagonists & inhibitors
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aSpleen
_xmetabolism
650 0 4 _aTissue Distribution
650 0 4 _aTreatment Outcome
650 0 4 _aTumor Necrosis Factor-alpha
_xantagonists & inhibitors
700 1 _aDey, I
700 1 _aTu , G C
700 1 _aZhou, F
700 1 _aAini, M
700 1 _aCao , Q N
700 1 _aIsrael, Y
773 0 _tThe Journal of pharmacology and experimental therapeutics
_gvol. 297
_gno. 3
_gp. 1129-36
999 _c11289081
_d11289081